Analgesic and Anti- Inflammatory Effects of Hydro Alcoholic Extract of (Syzygium aromaticum) in Albino Mice
The study was carried out to evaluate the analgesic and anti-inflammatory properties of an hydro alcoholic syzygium aromaticum extract (SAE) .The analgesic activity was measured by using the hot plate test with Twenty four (24) mice divided randomly into four groups , T1, T2 received 100 , 200 mg...
| Main Authors: | , , , , , |
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| Format: | Article |
| Sprog: | English |
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Faculty of Veterinary Medicine, University of Kufa
2017-12-01
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| Serier: | Kufa Journal for Veterinary Medical Sciences |
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| Online adgang: | https://journal.uokufa.edu.iq/index.php/kjvs/article/view/4124 |
| _version_ | 1827389137030742016 |
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| author | Ali Al-ameedi Jwad Faris Ali Rabee Hawraa Naji Amer Obayes Walaa Obaid |
| author_facet | Ali Al-ameedi Jwad Faris Ali Rabee Hawraa Naji Amer Obayes Walaa Obaid |
| author_sort | Ali Al-ameedi |
| collection | DOAJ |
| description | The study was carried out to evaluate the analgesic and anti-inflammatory properties of an hydro alcoholic syzygium aromaticum extract (SAE) .The analgesic activity was measured by using the hot plate test with Twenty four (24) mice divided randomly into four groups , T1, T2 received 100 , 200 mg /kg.bw of (SAE) while T3 dosed 50 mg /kg.bw of diclofanic acid and T4 used as control negative and dosed distilled water (D.W.) . The anti-inflammatory activity was measured by using formalin test with Twenty four (24) mice divided randomly into four groups , T1and T2 dosed with 100 and 200 mg /kg.bw respectively of (SAE) while T3 group dosed 0.3 mg/kg.bw of meloxicam and T4 dosed with (D.W.) , (all groups dosed orally before half hour of test) and then calculate the time of analgesia and anti-inflammatory effects . The result showed there is significant increase(p˂0.05) in time of analgesia and significant decreases (p˂0.05) in number of licking in animal exposed to (SAE) comparing with that of control , also there is significant increase(p˂0.05) in time of analgesia and decrease in licking in animals received diclofanic acid and meloxicam respectively comparing with those received (SAE) and D.W the increase was dose dependent manner. In conclusion the hydro-alcoholic extract of clove E.C showed analgesic and anti-inflammatory effect |
| first_indexed | 2024-03-08T16:30:06Z |
| format | Article |
| id | doaj.art-468f05ed0cb24851ac1739eda85c65cc |
| institution | Directory Open Access Journal |
| issn | 2077-9798 2959-8478 |
| language | English |
| last_indexed | 2024-03-08T16:30:06Z |
| publishDate | 2017-12-01 |
| publisher | Faculty of Veterinary Medicine, University of Kufa |
| record_format | Article |
| series | Kufa Journal for Veterinary Medical Sciences |
| spelling | doaj.art-468f05ed0cb24851ac1739eda85c65cc2024-01-06T10:13:18ZengFaculty of Veterinary Medicine, University of KufaKufa Journal for Veterinary Medical Sciences2077-97982959-84782017-12-018210.36326/kjvs/2017/v8i24124Analgesic and Anti- Inflammatory Effects of Hydro Alcoholic Extract of (Syzygium aromaticum) in Albino MiceAli Al-ameediJwad FarisAli RabeeHawraa NajiAmer ObayesWalaa ObaidThe study was carried out to evaluate the analgesic and anti-inflammatory properties of an hydro alcoholic syzygium aromaticum extract (SAE) .The analgesic activity was measured by using the hot plate test with Twenty four (24) mice divided randomly into four groups , T1, T2 received 100 , 200 mg /kg.bw of (SAE) while T3 dosed 50 mg /kg.bw of diclofanic acid and T4 used as control negative and dosed distilled water (D.W.) . The anti-inflammatory activity was measured by using formalin test with Twenty four (24) mice divided randomly into four groups , T1and T2 dosed with 100 and 200 mg /kg.bw respectively of (SAE) while T3 group dosed 0.3 mg/kg.bw of meloxicam and T4 dosed with (D.W.) , (all groups dosed orally before half hour of test) and then calculate the time of analgesia and anti-inflammatory effects . The result showed there is significant increase(p˂0.05) in time of analgesia and significant decreases (p˂0.05) in number of licking in animal exposed to (SAE) comparing with that of control , also there is significant increase(p˂0.05) in time of analgesia and decrease in licking in animals received diclofanic acid and meloxicam respectively comparing with those received (SAE) and D.W the increase was dose dependent manner. In conclusion the hydro-alcoholic extract of clove E.C showed analgesic and anti-inflammatory effecthttps://journal.uokufa.edu.iq/index.php/kjvs/article/view/4124Cloveformalin testhot plate test |
| spellingShingle | Ali Al-ameedi Jwad Faris Ali Rabee Hawraa Naji Amer Obayes Walaa Obaid Analgesic and Anti- Inflammatory Effects of Hydro Alcoholic Extract of (Syzygium aromaticum) in Albino Mice Kufa Journal for Veterinary Medical Sciences Clove formalin test hot plate test |
| title | Analgesic and Anti- Inflammatory Effects of Hydro Alcoholic Extract of (Syzygium aromaticum) in Albino Mice |
| title_full | Analgesic and Anti- Inflammatory Effects of Hydro Alcoholic Extract of (Syzygium aromaticum) in Albino Mice |
| title_fullStr | Analgesic and Anti- Inflammatory Effects of Hydro Alcoholic Extract of (Syzygium aromaticum) in Albino Mice |
| title_full_unstemmed | Analgesic and Anti- Inflammatory Effects of Hydro Alcoholic Extract of (Syzygium aromaticum) in Albino Mice |
| title_short | Analgesic and Anti- Inflammatory Effects of Hydro Alcoholic Extract of (Syzygium aromaticum) in Albino Mice |
| title_sort | analgesic and anti inflammatory effects of hydro alcoholic extract of syzygium aromaticum in albino mice |
| topic | Clove formalin test hot plate test |
| url | https://journal.uokufa.edu.iq/index.php/kjvs/article/view/4124 |
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