Cascade of access to interventions to prevent HIV mother to child transmission in the metropolitan area of Rio de Janeiro, Brazil
Objectives: To describe the access to the interventions for the prevention of Human Immunodeficiency Virus (HIV) mother to child transmission and mother to child transmission rates in the outskirts of Rio de Janeiro, from 1999 to 2009. Methods: This is a retrospective cohort study. Prevention of HIV...
| Main Authors: | , , , , , , , , , |
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| Format: | Article |
| Language: | English |
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Elsevier
2014-05-01
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| Series: | Brazilian Journal of Infectious Diseases |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S141386701300278X |
| _version_ | 1811207542077915136 |
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| author | Elaine S. Pires Araujo Ruth Khalili Friedman Luis Antonio Bastos Camacho Monica Derrico Ronaldo Ismério Moreira Guilherme Amaral Calvet Marília Santini de Oliveira Valdilea Gonçalves Veloso José Henrique Pilotto Beatriz Grinsztejn |
| author_facet | Elaine S. Pires Araujo Ruth Khalili Friedman Luis Antonio Bastos Camacho Monica Derrico Ronaldo Ismério Moreira Guilherme Amaral Calvet Marília Santini de Oliveira Valdilea Gonçalves Veloso José Henrique Pilotto Beatriz Grinsztejn |
| author_sort | Elaine S. Pires Araujo |
| collection | DOAJ |
| description | Objectives: To describe the access to the interventions for the prevention of Human Immunodeficiency Virus (HIV) mother to child transmission and mother to child transmission rates in the outskirts of Rio de Janeiro, from 1999 to 2009. Methods: This is a retrospective cohort study. Prevention of HIV mother to child transmission interventions were accessed and mother to child transmission rates were calculated. Results: The study population is young (median: 26 years; interquartile range: 22.0–31.0), with low monthly family income (40.4% up to one Brazilian minimum wage) and schooling (62.1% less than 8 years). Only 47.1% (n = 469) knew the HIV status of their partner; of these women, 39.9% had an HIV-seronegative partner. Among the 1259 newborns evaluated, access to the antenatal, intrapartum and postpartum prevention of HIV mother to child transmission components occurred in 59.2%, 74.2%, and 97.5% respectively; 91.0% of the newborns were not breastfed. Overall 52.7% of the newborns have benefited from all the recommended interventions. In subsequent pregnancies (n = 289), 67.8% of the newborns received the full package of interventions. The overall rate of HIV vertical transmission was 4.7% and the highest annual rate occurred in 2005 (7.4%), with no definite trend in the period. Conclusions: Access to the full package of interventions for the prevention of HIV vertical transmission was low, with no significant trend of improvement over the years. The vertical transmission rates observed were higher than those found in reference services in the municipality of Rio de Janeiro and in the richest regions of the country. Keywords: HIV, HIV vertical transmission, Antiretroviral chemoprophylaxis, Cohort studies, Brazil |
| first_indexed | 2024-04-12T04:06:21Z |
| format | Article |
| id | doaj.art-4690cd4995c240d19d7bdb089883af9a |
| institution | Directory Open Access Journal |
| issn | 1413-8670 |
| language | English |
| last_indexed | 2024-04-12T04:06:21Z |
| publishDate | 2014-05-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Brazilian Journal of Infectious Diseases |
| spelling | doaj.art-4690cd4995c240d19d7bdb089883af9a2022-12-22T03:48:36ZengElsevierBrazilian Journal of Infectious Diseases1413-86702014-05-01183252260S1413-86702014000300252Cascade of access to interventions to prevent HIV mother to child transmission in the metropolitan area of Rio de Janeiro, BrazilElaine S. Pires Araujo0Ruth Khalili Friedman1Luis Antonio Bastos Camacho2Monica Derrico3Ronaldo Ismério Moreira4Guilherme Amaral Calvet5Marília Santini de Oliveira6Valdilea Gonçalves Veloso7José Henrique Pilotto8Beatriz Grinsztejn9Laboratório de Pesquisa em DST/AIDS, Instituto de Pesquisa Clínica Evandro Chagas, Fundação Oswaldo Cruz (Fiocruz), Rio de Janeiro, RJ, Brazil; Hospital Geral de Nova Iguaçu, Serviço de DST/HIV/AIDS, Nova Iguaçu, Rio de Janeiro, RJ, Brazil; Corresponding author at: Laboratório de Pesquisa Clinica em DST/AIDS, Instituto de Pesquisa Clínica Evandro Chagas/IPEC, Rio de Janeiro, RJ, Brazil.Laboratório de Pesquisa em DST/AIDS, Instituto de Pesquisa Clínica Evandro Chagas, Fundação Oswaldo Cruz (Fiocruz), Rio de Janeiro, RJ, BrazilDepartamento de Epidemiologia e Métodos Quantitativos em Saúde, Escola Nacional de Saúde Publica, Fiocruz, Rio de Janeiro, RJ, BrazilLaboratório de Pesquisa em DST/AIDS, Instituto de Pesquisa Clínica Evandro Chagas, Fundação Oswaldo Cruz (Fiocruz), Rio de Janeiro, RJ, BrazilLaboratório de Pesquisa em DST/AIDS, Instituto de Pesquisa Clínica Evandro Chagas, Fundação Oswaldo Cruz (Fiocruz), Rio de Janeiro, RJ, BrazilLaboratório de Pesquisa em DST/AIDS, Instituto de Pesquisa Clínica Evandro Chagas, Fundação Oswaldo Cruz (Fiocruz), Rio de Janeiro, RJ, BrazilLaboratório de Pesquisa em DST/AIDS, Instituto de Pesquisa Clínica Evandro Chagas, Fundação Oswaldo Cruz (Fiocruz), Rio de Janeiro, RJ, BrazilLaboratório de Pesquisa em DST/AIDS, Instituto de Pesquisa Clínica Evandro Chagas, Fundação Oswaldo Cruz (Fiocruz), Rio de Janeiro, RJ, BrazilHospital Geral de Nova Iguaçu, Serviço de DST/HIV/AIDS, Nova Iguaçu, Rio de Janeiro, RJ, Brazil; Laboratório de AIDS e Imunologia Molecular, Instituto Oswaldo Cruz, Fiocruz, Rio de Janeiro, RJ, BrazilLaboratório de Pesquisa em DST/AIDS, Instituto de Pesquisa Clínica Evandro Chagas, Fundação Oswaldo Cruz (Fiocruz), Rio de Janeiro, RJ, BrazilObjectives: To describe the access to the interventions for the prevention of Human Immunodeficiency Virus (HIV) mother to child transmission and mother to child transmission rates in the outskirts of Rio de Janeiro, from 1999 to 2009. Methods: This is a retrospective cohort study. Prevention of HIV mother to child transmission interventions were accessed and mother to child transmission rates were calculated. Results: The study population is young (median: 26 years; interquartile range: 22.0–31.0), with low monthly family income (40.4% up to one Brazilian minimum wage) and schooling (62.1% less than 8 years). Only 47.1% (n = 469) knew the HIV status of their partner; of these women, 39.9% had an HIV-seronegative partner. Among the 1259 newborns evaluated, access to the antenatal, intrapartum and postpartum prevention of HIV mother to child transmission components occurred in 59.2%, 74.2%, and 97.5% respectively; 91.0% of the newborns were not breastfed. Overall 52.7% of the newborns have benefited from all the recommended interventions. In subsequent pregnancies (n = 289), 67.8% of the newborns received the full package of interventions. The overall rate of HIV vertical transmission was 4.7% and the highest annual rate occurred in 2005 (7.4%), with no definite trend in the period. Conclusions: Access to the full package of interventions for the prevention of HIV vertical transmission was low, with no significant trend of improvement over the years. The vertical transmission rates observed were higher than those found in reference services in the municipality of Rio de Janeiro and in the richest regions of the country. Keywords: HIV, HIV vertical transmission, Antiretroviral chemoprophylaxis, Cohort studies, Brazilhttp://www.sciencedirect.com/science/article/pii/S141386701300278X |
| spellingShingle | Elaine S. Pires Araujo Ruth Khalili Friedman Luis Antonio Bastos Camacho Monica Derrico Ronaldo Ismério Moreira Guilherme Amaral Calvet Marília Santini de Oliveira Valdilea Gonçalves Veloso José Henrique Pilotto Beatriz Grinsztejn Cascade of access to interventions to prevent HIV mother to child transmission in the metropolitan area of Rio de Janeiro, Brazil Brazilian Journal of Infectious Diseases |
| title | Cascade of access to interventions to prevent HIV mother to child transmission in the metropolitan area of Rio de Janeiro, Brazil |
| title_full | Cascade of access to interventions to prevent HIV mother to child transmission in the metropolitan area of Rio de Janeiro, Brazil |
| title_fullStr | Cascade of access to interventions to prevent HIV mother to child transmission in the metropolitan area of Rio de Janeiro, Brazil |
| title_full_unstemmed | Cascade of access to interventions to prevent HIV mother to child transmission in the metropolitan area of Rio de Janeiro, Brazil |
| title_short | Cascade of access to interventions to prevent HIV mother to child transmission in the metropolitan area of Rio de Janeiro, Brazil |
| title_sort | cascade of access to interventions to prevent hiv mother to child transmission in the metropolitan area of rio de janeiro brazil |
| url | http://www.sciencedirect.com/science/article/pii/S141386701300278X |
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