Poor quality sleep is associated with greater carotid intima media thickness among otherwise healthy resident doctors
BackgroundSleep is important for maintaining the metabolic processes in the body, and hence, disruption in sleep leads to metabolic derangement and accelerated atherosclerosis. The effect of sleep duration on subclinical atherosclerosis has been examined in several studies; however, data regarding s...
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2023-01-01
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| Series: | Frontiers in Epidemiology |
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| Online Access: | https://www.frontiersin.org/articles/10.3389/fepid.2022.1044111/full |
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| author | Prativa Priyadarshani Sethi Monika Pathania Ravi Gupta Pankaj Sharma Lokesh Kumar Saini |
| author_facet | Prativa Priyadarshani Sethi Monika Pathania Ravi Gupta Pankaj Sharma Lokesh Kumar Saini |
| author_sort | Prativa Priyadarshani Sethi |
| collection | DOAJ |
| description | BackgroundSleep is important for maintaining the metabolic processes in the body, and hence, disruption in sleep leads to metabolic derangement and accelerated atherosclerosis. The effect of sleep duration on subclinical atherosclerosis has been examined in several studies; however, data regarding sleep quality is lacking. The study aimed to assess the association between sleep quality and carotid intima-media thickness among healthy young doctors.Materials and MethodsThis was an observational cross-sectional study among 110 healthy young resident doctors. Anthropometric data were recorded and morning fasting venous blood samples were collected to assess fasting blood sugar, lipid profile and glycosylated haemoglobin (HbA1c). Pittsburgh Sleep Quality Index and Berlin questionnaire assessed subjective sleep quality and risk for obstructive sleep apnea, respectively. Carotid ultrasonography was done to detect the intima-media thickness.ResultsAverage age of the participants was 26.45 (±1.43) years, and 51.8% were male. Self-reported poor sleep quality was found in 54.5%. Carotid intima-media thickness (CIMT) was increased among 44.5% of participants. In the multivariate analysis, only poor sleep quality appeared to be associated with higher CIMT (P < 0.001, OR = 7.4; 95% CI = 2.70–20.32). When different components of sleep quality was analyzed through multivariate logistic regression, subjective sleep onset latency (>30 min), sleep efficiency (<85%) and sleep disturbance was found to be associated with the increased CIMT.ConclusionPoor sleep quality, especially prolonged sleep onset latency, poor sleep efficiency, and sleep disturbance are associated with increased carotid intima-media thickness among healthy young adults. |
| first_indexed | 2024-04-10T23:44:34Z |
| format | Article |
| id | doaj.art-4692892d98c4446b8add2ec93f91e304 |
| institution | Directory Open Access Journal |
| issn | 2674-1199 |
| language | English |
| last_indexed | 2024-04-10T23:44:34Z |
| publishDate | 2023-01-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Epidemiology |
| spelling | doaj.art-4692892d98c4446b8add2ec93f91e3042023-01-11T05:24:03ZengFrontiers Media S.A.Frontiers in Epidemiology2674-11992023-01-01210.3389/fepid.2022.10441111044111Poor quality sleep is associated with greater carotid intima media thickness among otherwise healthy resident doctorsPrativa Priyadarshani Sethi0Monika Pathania1Ravi Gupta2Pankaj Sharma3Lokesh Kumar Saini4Department of Internal Medicine, All India Institute of Medical Science, Rishikesh, IndiaDepartment of Internal Medicine, All India Institute of Medical Science, Rishikesh, IndiaDepartment of Psychiatry, All India Institute of Medical Science, Rishikesh, IndiaDepartment of Radiodiagnosis, All India Institute of Medical Science, Rishikesh, IndiaDepartment of Pulmonary Medicine, All India Institute of Medical Science, Rishikesh, IndiaBackgroundSleep is important for maintaining the metabolic processes in the body, and hence, disruption in sleep leads to metabolic derangement and accelerated atherosclerosis. The effect of sleep duration on subclinical atherosclerosis has been examined in several studies; however, data regarding sleep quality is lacking. The study aimed to assess the association between sleep quality and carotid intima-media thickness among healthy young doctors.Materials and MethodsThis was an observational cross-sectional study among 110 healthy young resident doctors. Anthropometric data were recorded and morning fasting venous blood samples were collected to assess fasting blood sugar, lipid profile and glycosylated haemoglobin (HbA1c). Pittsburgh Sleep Quality Index and Berlin questionnaire assessed subjective sleep quality and risk for obstructive sleep apnea, respectively. Carotid ultrasonography was done to detect the intima-media thickness.ResultsAverage age of the participants was 26.45 (±1.43) years, and 51.8% were male. Self-reported poor sleep quality was found in 54.5%. Carotid intima-media thickness (CIMT) was increased among 44.5% of participants. In the multivariate analysis, only poor sleep quality appeared to be associated with higher CIMT (P < 0.001, OR = 7.4; 95% CI = 2.70–20.32). When different components of sleep quality was analyzed through multivariate logistic regression, subjective sleep onset latency (>30 min), sleep efficiency (<85%) and sleep disturbance was found to be associated with the increased CIMT.ConclusionPoor sleep quality, especially prolonged sleep onset latency, poor sleep efficiency, and sleep disturbance are associated with increased carotid intima-media thickness among healthy young adults.https://www.frontiersin.org/articles/10.3389/fepid.2022.1044111/fullphysician healthsubclinical atherosclerosissleep hygienesleep medicinecardiovascular medicine |
| spellingShingle | Prativa Priyadarshani Sethi Monika Pathania Ravi Gupta Pankaj Sharma Lokesh Kumar Saini Poor quality sleep is associated with greater carotid intima media thickness among otherwise healthy resident doctors Frontiers in Epidemiology physician health subclinical atherosclerosis sleep hygiene sleep medicine cardiovascular medicine |
| title | Poor quality sleep is associated with greater carotid intima media thickness among otherwise healthy resident doctors |
| title_full | Poor quality sleep is associated with greater carotid intima media thickness among otherwise healthy resident doctors |
| title_fullStr | Poor quality sleep is associated with greater carotid intima media thickness among otherwise healthy resident doctors |
| title_full_unstemmed | Poor quality sleep is associated with greater carotid intima media thickness among otherwise healthy resident doctors |
| title_short | Poor quality sleep is associated with greater carotid intima media thickness among otherwise healthy resident doctors |
| title_sort | poor quality sleep is associated with greater carotid intima media thickness among otherwise healthy resident doctors |
| topic | physician health subclinical atherosclerosis sleep hygiene sleep medicine cardiovascular medicine |
| url | https://www.frontiersin.org/articles/10.3389/fepid.2022.1044111/full |
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