Metabolic Characterization and Consequences of Mitochondrial Pyruvate Carrier Deficiency in <i>Drosophila melanogaster</i>

Metabolic Characterization and Consequences of Mitochondrial Pyruvate Carrier Deficiency in <i>Drosophila melanogaster</i>

In insect, pyruvate is generally the predominant oxidative substrate for mitochondria. This metabolite is transported inside mitochondria via the mitochondrial pyruvate carrier (MPC), but whether and how this transporter controls mitochondrial oxidative capacities in insects is still relatively unkn...

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Bibliographic Details
Main Authors: Chloé Simard, Andréa Lebel, Eric Pierre Allain, Mohamed Touaibia, Etienne Hebert-Chatelain, Nicolas Pichaud
Format: Article
Language:English
Published: MDPI AG 2020-09-01
Series:Metabolites
Subjects:
drosophila
kinetics
metabolomics
mitochondrial pyruvate carrier
mitochondrial respiration
Online Access:https://www.mdpi.com/2218-1989/10/9/363

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