Trends in Life Expectancy of Cystic Fibrosis Patients in Moscow and their Connection with the Treatment Received: Retrospective Analysis for 1993–2013
Cystic fibrosis is multiple organ pathology that requires a complex treatment. Its standardization and pharmacoeconomic analysis are absolutely necessary. We performed a retrospective analysis of the trends in life expectancy of cystic fibrosis patients who lived inMoscow in 1993, 1998, 2003, 2008,...
| Main Authors: | , , , , , , , , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
"Paediatrician" Publishers LLC
2015-09-01
|
| Series: | Вопросы современной педиатрии |
| Subjects: | |
| Online Access: | https://vsp.spr-journal.ru/jour/article/view/1083 |
| _version_ | 1797694932715044864 |
|---|---|
| author | N. Yu. Kashirskaya S. A. Krasovsky A. V. Chernyak V. D. Sherman A. Yu. Voronkova L. A. Shabalova V. S. Nikonova Yu. V. Gorinova O. I. Simonova E. L. Amelina E. I. Kondrat’eva N. I. Kapranov N. V. Petrova R. A. Zinchenko |
| author_facet | N. Yu. Kashirskaya S. A. Krasovsky A. V. Chernyak V. D. Sherman A. Yu. Voronkova L. A. Shabalova V. S. Nikonova Yu. V. Gorinova O. I. Simonova E. L. Amelina E. I. Kondrat’eva N. I. Kapranov N. V. Petrova R. A. Zinchenko |
| author_sort | N. Yu. Kashirskaya |
| collection | DOAJ |
| description | Cystic fibrosis is multiple organ pathology that requires a complex treatment. Its standardization and pharmacoeconomic analysis are absolutely necessary. We performed a retrospective analysis of the trends in life expectancy of cystic fibrosis patients who lived inMoscow in 1993, 1998, 2003, 2008, and 2013. It was found that the survival rate of these patients depended on the choice of drug therapy (pancreatic enzymes, dornase alfa, intravenous and inhaled antipseudomonal antibiotics), changes in diet, active dispensary observation at a specialized center for cystic fibrosis, and neonatal screening. We determined the cost of drug therapy per patient. From 1993 to 2013, the survival rate of patients who lived in Moscow increased by more than 20 years (from 16 to 39 years, respectively). The average cost of therapy increased more than 10 times (from USD 1.8 to 21.9 thousand, respectively). |
| first_indexed | 2024-03-12T03:05:01Z |
| format | Article |
| id | doaj.art-469ac005c5ab44a3b76219cbd0d47e2f |
| institution | Directory Open Access Journal |
| issn | 1682-5527 1682-5535 |
| language | English |
| last_indexed | 2024-03-12T03:05:01Z |
| publishDate | 2015-09-01 |
| publisher | "Paediatrician" Publishers LLC |
| record_format | Article |
| series | Вопросы современной педиатрии |
| spelling | doaj.art-469ac005c5ab44a3b76219cbd0d47e2f2023-09-03T14:32:58Zeng"Paediatrician" Publishers LLCВопросы современной педиатрии1682-55271682-55352015-09-0114450350810.15690/vsp.v14.i4.13901084Trends in Life Expectancy of Cystic Fibrosis Patients in Moscow and their Connection with the Treatment Received: Retrospective Analysis for 1993–2013N. Yu. Kashirskaya0S. A. Krasovsky1A. V. Chernyak2V. D. Sherman3A. Yu. Voronkova4L. A. Shabalova5V. S. Nikonova6Yu. V. Gorinova7O. I. Simonova8E. L. Amelina9E. I. Kondrat’eva10N. I. Kapranov11N. V. Petrova12R. A. Zinchenko13Медико-генетический научный центр, Москва, Российская ФедерацияНИИ пульмонологии, Москва, Российская ФедерацияНИИ пульмонологии, Москва, Российская ФедерацияМедико-генетический научный центр, Москва, Российская ФедерацияМедико-генетический научный центр, Москва, Российская ФедерацияМедико-генетический научный центр, Москва, Российская ФедерацияМедико-генетический научный центр, Москва, Российская ФедерацияНаучный центр здоровья детей, Москва, Российская ФедерацияНаучный центр здоровья детей, Москва, Российская ФедерацияНИИ пульмонологии, Москва, Российская ФедерацияМедико-генетический научный центр, Москва, Российская ФедерацияМедико-генетический научный центр, Москва, Российская ФедерацияМедико-генетический научный центр, Москва, Российская ФедерацияМедико-генетический научный центр, Москва, Российская Федерация Московский государственный медико-стоматологический университет им. А.И. Евдокимова, Москва, Российская ФедерацияCystic fibrosis is multiple organ pathology that requires a complex treatment. Its standardization and pharmacoeconomic analysis are absolutely necessary. We performed a retrospective analysis of the trends in life expectancy of cystic fibrosis patients who lived inMoscow in 1993, 1998, 2003, 2008, and 2013. It was found that the survival rate of these patients depended on the choice of drug therapy (pancreatic enzymes, dornase alfa, intravenous and inhaled antipseudomonal antibiotics), changes in diet, active dispensary observation at a specialized center for cystic fibrosis, and neonatal screening. We determined the cost of drug therapy per patient. From 1993 to 2013, the survival rate of patients who lived in Moscow increased by more than 20 years (from 16 to 39 years, respectively). The average cost of therapy increased more than 10 times (from USD 1.8 to 21.9 thousand, respectively).https://vsp.spr-journal.ru/jour/article/view/1083муковисцидозвыживаемостьлечениестоимостьдорназа альфа |
| spellingShingle | N. Yu. Kashirskaya S. A. Krasovsky A. V. Chernyak V. D. Sherman A. Yu. Voronkova L. A. Shabalova V. S. Nikonova Yu. V. Gorinova O. I. Simonova E. L. Amelina E. I. Kondrat’eva N. I. Kapranov N. V. Petrova R. A. Zinchenko Trends in Life Expectancy of Cystic Fibrosis Patients in Moscow and their Connection with the Treatment Received: Retrospective Analysis for 1993–2013 Вопросы современной педиатрии муковисцидоз выживаемость лечение стоимость дорназа альфа |
| title | Trends in Life Expectancy of Cystic Fibrosis Patients in Moscow and their Connection with the Treatment Received: Retrospective Analysis for 1993–2013 |
| title_full | Trends in Life Expectancy of Cystic Fibrosis Patients in Moscow and their Connection with the Treatment Received: Retrospective Analysis for 1993–2013 |
| title_fullStr | Trends in Life Expectancy of Cystic Fibrosis Patients in Moscow and their Connection with the Treatment Received: Retrospective Analysis for 1993–2013 |
| title_full_unstemmed | Trends in Life Expectancy of Cystic Fibrosis Patients in Moscow and their Connection with the Treatment Received: Retrospective Analysis for 1993–2013 |
| title_short | Trends in Life Expectancy of Cystic Fibrosis Patients in Moscow and their Connection with the Treatment Received: Retrospective Analysis for 1993–2013 |
| title_sort | trends in life expectancy of cystic fibrosis patients in moscow and their connection with the treatment received retrospective analysis for 1993 2013 |
| topic | муковисцидоз выживаемость лечение стоимость дорназа альфа |
| url | https://vsp.spr-journal.ru/jour/article/view/1083 |
| work_keys_str_mv | AT nyukashirskaya trendsinlifeexpectancyofcysticfibrosispatientsinmoscowandtheirconnectionwiththetreatmentreceivedretrospectiveanalysisfor19932013 AT sakrasovsky trendsinlifeexpectancyofcysticfibrosispatientsinmoscowandtheirconnectionwiththetreatmentreceivedretrospectiveanalysisfor19932013 AT avchernyak trendsinlifeexpectancyofcysticfibrosispatientsinmoscowandtheirconnectionwiththetreatmentreceivedretrospectiveanalysisfor19932013 AT vdsherman trendsinlifeexpectancyofcysticfibrosispatientsinmoscowandtheirconnectionwiththetreatmentreceivedretrospectiveanalysisfor19932013 AT ayuvoronkova trendsinlifeexpectancyofcysticfibrosispatientsinmoscowandtheirconnectionwiththetreatmentreceivedretrospectiveanalysisfor19932013 AT lashabalova trendsinlifeexpectancyofcysticfibrosispatientsinmoscowandtheirconnectionwiththetreatmentreceivedretrospectiveanalysisfor19932013 AT vsnikonova trendsinlifeexpectancyofcysticfibrosispatientsinmoscowandtheirconnectionwiththetreatmentreceivedretrospectiveanalysisfor19932013 AT yuvgorinova trendsinlifeexpectancyofcysticfibrosispatientsinmoscowandtheirconnectionwiththetreatmentreceivedretrospectiveanalysisfor19932013 AT oisimonova trendsinlifeexpectancyofcysticfibrosispatientsinmoscowandtheirconnectionwiththetreatmentreceivedretrospectiveanalysisfor19932013 AT elamelina trendsinlifeexpectancyofcysticfibrosispatientsinmoscowandtheirconnectionwiththetreatmentreceivedretrospectiveanalysisfor19932013 AT eikondrateva trendsinlifeexpectancyofcysticfibrosispatientsinmoscowandtheirconnectionwiththetreatmentreceivedretrospectiveanalysisfor19932013 AT nikapranov trendsinlifeexpectancyofcysticfibrosispatientsinmoscowandtheirconnectionwiththetreatmentreceivedretrospectiveanalysisfor19932013 AT nvpetrova trendsinlifeexpectancyofcysticfibrosispatientsinmoscowandtheirconnectionwiththetreatmentreceivedretrospectiveanalysisfor19932013 AT razinchenko trendsinlifeexpectancyofcysticfibrosispatientsinmoscowandtheirconnectionwiththetreatmentreceivedretrospectiveanalysisfor19932013 |