Optical Coherence Tomography Angiography Findings in Long-Term Follow-up of Leber’s Hereditary Optic Neuropathy: Report of Two Cases
Leber’s hereditary optic neuropathy (LHON) is thought to be a neurovascular disease due to presence of vascular changes in asymptomatic patients. Here we present 2 patients in whom optical coherence tomography angiography (OCTA) imaging demonstrated capillary drop-out areas and decreased radial peri...
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| Format: | Article |
| Language: | English |
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Galenos Yayinevi
2020-10-01
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| Series: | Türk Oftalmoloji Dergisi |
| Subjects: | |
| Online Access: |
http://www.oftalmoloji.org/archives/archive-detail/article-preview/optical-coherence-tomography-angiography-findings-/41737
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| _version_ | 1797922941794516992 |
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| author | Pınar Bingöl Kızıltunç Feyza Tüntaş Bilen Huban Atilla |
| author_facet | Pınar Bingöl Kızıltunç Feyza Tüntaş Bilen Huban Atilla |
| author_sort | Pınar Bingöl Kızıltunç |
| collection | DOAJ |
| description | Leber’s hereditary optic neuropathy (LHON) is thought to be a neurovascular disease due to presence of vascular changes in asymptomatic patients. Here we present 2 patients in whom optical coherence tomography angiography (OCTA) imaging demonstrated capillary drop-out areas and decreased radial peripapillary capillary (RPC) density in the quadrants that had thinner retinal nerve fiber layer (RNFL) in OCT images. Progressive decrease in RNFL and RPC density were shown in each patient at month 12 and 30 of follow-up. Following up patients with OCTA imaging in the future will provide insight into the pathogenesis and prognosis of LHON. |
| first_indexed | 2024-04-10T14:40:12Z |
| format | Article |
| id | doaj.art-46a4e5e9318a4d38a48e4edfd4def243 |
| institution | Directory Open Access Journal |
| issn | 1300-0659 2147-2661 |
| language | English |
| last_indexed | 2024-04-10T14:40:12Z |
| publishDate | 2020-10-01 |
| publisher | Galenos Yayinevi |
| record_format | Article |
| series | Türk Oftalmoloji Dergisi |
| spelling | doaj.art-46a4e5e9318a4d38a48e4edfd4def2432023-02-15T16:08:15ZengGalenos YayineviTürk Oftalmoloji Dergisi1300-06592147-26612020-10-0150531331610.4274/tjo.galenos.2020.8630013049054Optical Coherence Tomography Angiography Findings in Long-Term Follow-up of Leber’s Hereditary Optic Neuropathy: Report of Two CasesPınar Bingöl Kızıltunç0Feyza Tüntaş Bilen1Huban Atilla2 Ankara Üniversitesi Tıp Fakültesi, Göz Hastalıkları Anabilim Dalı, Ankara, Türkiye Haymana Devlet Hastanesi, Göz Hastalıkları Kliniği, Ankara, Türkiye Ankara Üniversitesi Tıp Fakültesi, Göz Hastalıkları Anabilim Dalı, Ankara, Türkiye Leber’s hereditary optic neuropathy (LHON) is thought to be a neurovascular disease due to presence of vascular changes in asymptomatic patients. Here we present 2 patients in whom optical coherence tomography angiography (OCTA) imaging demonstrated capillary drop-out areas and decreased radial peripapillary capillary (RPC) density in the quadrants that had thinner retinal nerve fiber layer (RNFL) in OCT images. Progressive decrease in RNFL and RPC density were shown in each patient at month 12 and 30 of follow-up. Following up patients with OCTA imaging in the future will provide insight into the pathogenesis and prognosis of LHON. http://www.oftalmoloji.org/archives/archive-detail/article-preview/optical-coherence-tomography-angiography-findings-/41737 leber’s hereditary optic neuropathyoptical coherence tomographyoptical coherence tomography angiographyretinal nerve fiber layer |
| spellingShingle | Pınar Bingöl Kızıltunç Feyza Tüntaş Bilen Huban Atilla Optical Coherence Tomography Angiography Findings in Long-Term Follow-up of Leber’s Hereditary Optic Neuropathy: Report of Two Cases Türk Oftalmoloji Dergisi leber’s hereditary optic neuropathy optical coherence tomography optical coherence tomography angiography retinal nerve fiber layer |
| title | Optical Coherence Tomography Angiography Findings in Long-Term Follow-up of Leber’s Hereditary Optic Neuropathy: Report of Two Cases |
| title_full | Optical Coherence Tomography Angiography Findings in Long-Term Follow-up of Leber’s Hereditary Optic Neuropathy: Report of Two Cases |
| title_fullStr | Optical Coherence Tomography Angiography Findings in Long-Term Follow-up of Leber’s Hereditary Optic Neuropathy: Report of Two Cases |
| title_full_unstemmed | Optical Coherence Tomography Angiography Findings in Long-Term Follow-up of Leber’s Hereditary Optic Neuropathy: Report of Two Cases |
| title_short | Optical Coherence Tomography Angiography Findings in Long-Term Follow-up of Leber’s Hereditary Optic Neuropathy: Report of Two Cases |
| title_sort | optical coherence tomography angiography findings in long term follow up of leber s hereditary optic neuropathy report of two cases |
| topic | leber’s hereditary optic neuropathy optical coherence tomography optical coherence tomography angiography retinal nerve fiber layer |
| url |
http://www.oftalmoloji.org/archives/archive-detail/article-preview/optical-coherence-tomography-angiography-findings-/41737
|
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