Contemporary Evaluation and Clinical Treatment Options for Aortic Regurgitation
Aortic regurgitation (AR) is the third most frequent form of valvular disease and has increasing prevalence with age. This will be of increasing clinical importance with the advancing age of populations around the globe. An understanding of the various etiologies and mechanisms leading to AR require...
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| Format: | Article |
| Language: | English |
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MDPI AG
2023-08-01
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| Series: | Journal of Cardiovascular Development and Disease |
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| Online Access: | https://www.mdpi.com/2308-3425/10/9/364 |
| _version_ | 1797579500506054656 |
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| author | Mark Lebehn Torsten Vahl Polydoros Kampaktsis Rebecca T. Hahn |
| author_facet | Mark Lebehn Torsten Vahl Polydoros Kampaktsis Rebecca T. Hahn |
| author_sort | Mark Lebehn |
| collection | DOAJ |
| description | Aortic regurgitation (AR) is the third most frequent form of valvular disease and has increasing prevalence with age. This will be of increasing clinical importance with the advancing age of populations around the globe. An understanding of the various etiologies and mechanisms leading to AR requires a detailed understanding of the structure of the aortic valve and aortic root. While acute and chronic AR may share a similar etiology, their hemodynamic impact on the left ventricle (LV) and management are very different. Recent studies suggest current guideline recommendations for chronic disease may result in late intervention and suboptimal outcomes. Accurate quantitation of ventricular size and function, as well as grading of the severity of regurgitation, requires a multiparametric and multimodality imaging approach with an understanding of the strengths and weaknesses of each metric. Echocardiography remains the primary imaging modality for diagnosis with supplemental information provided by computed tomography (CT) and cardiac magnetic resonance imaging (CMR). Emerging transcatheter therapies may allow the treatment of patients at high risk for surgery, although novel methods to assess AR severity and its impact on LV size and function may improve the timing and outcomes of surgical intervention. |
| first_indexed | 2024-03-10T22:38:03Z |
| format | Article |
| id | doaj.art-46a62ac6c5074e9ca044ac894642a10a |
| institution | Directory Open Access Journal |
| issn | 2308-3425 |
| language | English |
| last_indexed | 2024-03-10T22:38:03Z |
| publishDate | 2023-08-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Journal of Cardiovascular Development and Disease |
| spelling | doaj.art-46a62ac6c5074e9ca044ac894642a10a2023-11-19T11:16:23ZengMDPI AGJournal of Cardiovascular Development and Disease2308-34252023-08-0110936410.3390/jcdd10090364Contemporary Evaluation and Clinical Treatment Options for Aortic RegurgitationMark Lebehn0Torsten Vahl1Polydoros Kampaktsis2Rebecca T. Hahn3Department of Medicine, Columbia University Irving Medical Center, New York, NY 10032, USADepartment of Medicine, Columbia University Irving Medical Center, New York, NY 10032, USADepartment of Medicine, Columbia University Irving Medical Center, New York, NY 10032, USADepartment of Medicine, Columbia University Irving Medical Center, New York, NY 10032, USAAortic regurgitation (AR) is the third most frequent form of valvular disease and has increasing prevalence with age. This will be of increasing clinical importance with the advancing age of populations around the globe. An understanding of the various etiologies and mechanisms leading to AR requires a detailed understanding of the structure of the aortic valve and aortic root. While acute and chronic AR may share a similar etiology, their hemodynamic impact on the left ventricle (LV) and management are very different. Recent studies suggest current guideline recommendations for chronic disease may result in late intervention and suboptimal outcomes. Accurate quantitation of ventricular size and function, as well as grading of the severity of regurgitation, requires a multiparametric and multimodality imaging approach with an understanding of the strengths and weaknesses of each metric. Echocardiography remains the primary imaging modality for diagnosis with supplemental information provided by computed tomography (CT) and cardiac magnetic resonance imaging (CMR). Emerging transcatheter therapies may allow the treatment of patients at high risk for surgery, although novel methods to assess AR severity and its impact on LV size and function may improve the timing and outcomes of surgical intervention.https://www.mdpi.com/2308-3425/10/9/364aortic regurgitationechocardiographytranscatheter aortic valve replacement |
| spellingShingle | Mark Lebehn Torsten Vahl Polydoros Kampaktsis Rebecca T. Hahn Contemporary Evaluation and Clinical Treatment Options for Aortic Regurgitation Journal of Cardiovascular Development and Disease aortic regurgitation echocardiography transcatheter aortic valve replacement |
| title | Contemporary Evaluation and Clinical Treatment Options for Aortic Regurgitation |
| title_full | Contemporary Evaluation and Clinical Treatment Options for Aortic Regurgitation |
| title_fullStr | Contemporary Evaluation and Clinical Treatment Options for Aortic Regurgitation |
| title_full_unstemmed | Contemporary Evaluation and Clinical Treatment Options for Aortic Regurgitation |
| title_short | Contemporary Evaluation and Clinical Treatment Options for Aortic Regurgitation |
| title_sort | contemporary evaluation and clinical treatment options for aortic regurgitation |
| topic | aortic regurgitation echocardiography transcatheter aortic valve replacement |
| url | https://www.mdpi.com/2308-3425/10/9/364 |
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