Ultra high resolution optical coherence tomography in Boston type I keratoprosthesis
Purpose: To evaluate the anterior keratoprosthesis-cornea interface in eyes with Boston type I keratoprosthesis (Kpro). Methods: In a prospective non-interventional study, patients with Boston type I Kpro underwent ultra-high resolution optical coherence tomography (UHR-OCT) evaluation. The images...
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| Format: | Article |
| Language: | English |
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Knowledge E
2015-01-01
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| Series: | Journal of Ophthalmic & Vision Research |
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| Online Access: | http://www.jovr.org/article.asp?issn=2008-322X;year=2015;volume=10;issue=1;spage=26;epage=32;aulast=Zarei-Ghanavati |
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| author | Siamak Zarei-Ghanavati Carolina Betancurt Alma Michelle Mas Jianhua Wang Victor L Perez |
| author_facet | Siamak Zarei-Ghanavati Carolina Betancurt Alma Michelle Mas Jianhua Wang Victor L Perez |
| author_sort | Siamak Zarei-Ghanavati |
| collection | DOAJ |
| description | Purpose: To evaluate the anterior keratoprosthesis-cornea interface in eyes with Boston type I keratoprosthesis (Kpro).
Methods: In a prospective non-interventional study, patients with Boston type I Kpro underwent ultra-high resolution optical coherence tomography (UHR-OCT) evaluation. The images were used to measure and describe characteristics of the anterior keratoprosthesis-cornea interface, epithelial interaction at the keratoprosthesis edge and the keratoprosthesis-cornea interface gap.
Results: Ten patients including 4 male and 6 female subjects with different preoperative diagnoses, i.e. 8 multiple corneal graft failures and 2 immunological ocular surface diseases, were studied. Mean age was 62.1 ± 20.0 (range, 33.0-83.0) years and mean interval between surgery and UHR-OCT evaluation was 15.2 ± 11.09 months. In eight patients, 360° epithelial growth over the peripheral edge of the Kpro was documented. We detected keratoprosthesis-cornea interface gap in three patients. One subject had developed postoperative endophthalmitis 8 months after surgery and the other two cases were among the high risk group according to the preoperative diagnosis. In one patient with severe ocular hypotony, the Kpro edge was inserted into the anterior stroma and covered with epithelium.
Conclusion: UHR-OCT showed that corneal epithelium covers the Kpro edge and seals the potential space between the Kpro and cornea in 80% of cases. The presence of a gap in the interface and lack of epithelial sealing around the Kpro edge might be associated with endophthalmitis. |
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| format | Article |
| id | doaj.art-46a731026d4d46599452fe86bc5488a8 |
| institution | Directory Open Access Journal |
| issn | 2008-322X |
| language | English |
| last_indexed | 2024-04-13T14:22:58Z |
| publishDate | 2015-01-01 |
| publisher | Knowledge E |
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| series | Journal of Ophthalmic & Vision Research |
| spelling | doaj.art-46a731026d4d46599452fe86bc5488a82022-12-22T02:43:25ZengKnowledge EJournal of Ophthalmic & Vision Research2008-322X2015-01-01101263210.4103/2008-322X.156092Ultra high resolution optical coherence tomography in Boston type I keratoprosthesisSiamak Zarei-GhanavatiCarolina BetancurtAlma Michelle MasJianhua WangVictor L PerezPurpose: To evaluate the anterior keratoprosthesis-cornea interface in eyes with Boston type I keratoprosthesis (Kpro). Methods: In a prospective non-interventional study, patients with Boston type I Kpro underwent ultra-high resolution optical coherence tomography (UHR-OCT) evaluation. The images were used to measure and describe characteristics of the anterior keratoprosthesis-cornea interface, epithelial interaction at the keratoprosthesis edge and the keratoprosthesis-cornea interface gap. Results: Ten patients including 4 male and 6 female subjects with different preoperative diagnoses, i.e. 8 multiple corneal graft failures and 2 immunological ocular surface diseases, were studied. Mean age was 62.1 ± 20.0 (range, 33.0-83.0) years and mean interval between surgery and UHR-OCT evaluation was 15.2 ± 11.09 months. In eight patients, 360° epithelial growth over the peripheral edge of the Kpro was documented. We detected keratoprosthesis-cornea interface gap in three patients. One subject had developed postoperative endophthalmitis 8 months after surgery and the other two cases were among the high risk group according to the preoperative diagnosis. In one patient with severe ocular hypotony, the Kpro edge was inserted into the anterior stroma and covered with epithelium. Conclusion: UHR-OCT showed that corneal epithelium covers the Kpro edge and seals the potential space between the Kpro and cornea in 80% of cases. The presence of a gap in the interface and lack of epithelial sealing around the Kpro edge might be associated with endophthalmitis.http://www.jovr.org/article.asp?issn=2008-322X;year=2015;volume=10;issue=1;spage=26;epage=32;aulast=Zarei-GhanavatiAnterior Segment OCT; Boston Type I Keratoprosthesis; Ultra High-resolution OCT |
| spellingShingle | Siamak Zarei-Ghanavati Carolina Betancurt Alma Michelle Mas Jianhua Wang Victor L Perez Ultra high resolution optical coherence tomography in Boston type I keratoprosthesis Journal of Ophthalmic & Vision Research Anterior Segment OCT; Boston Type I Keratoprosthesis; Ultra High-resolution OCT |
| title | Ultra high resolution optical coherence tomography in Boston type I keratoprosthesis |
| title_full | Ultra high resolution optical coherence tomography in Boston type I keratoprosthesis |
| title_fullStr | Ultra high resolution optical coherence tomography in Boston type I keratoprosthesis |
| title_full_unstemmed | Ultra high resolution optical coherence tomography in Boston type I keratoprosthesis |
| title_short | Ultra high resolution optical coherence tomography in Boston type I keratoprosthesis |
| title_sort | ultra high resolution optical coherence tomography in boston type i keratoprosthesis |
| topic | Anterior Segment OCT; Boston Type I Keratoprosthesis; Ultra High-resolution OCT |
| url | http://www.jovr.org/article.asp?issn=2008-322X;year=2015;volume=10;issue=1;spage=26;epage=32;aulast=Zarei-Ghanavati |
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