Type XXII Collagen Complements Fibrillar Collagens in the Serological Assessment of Tumor Fibrosis and the Outcome in Pancreatic Cancer

Type XXII Collagen Complements Fibrillar Collagens in the Serological Assessment of Tumor Fibrosis and the Outcome in Pancreatic Cancer

Circulating fragments of type III collagen, measured by PRO-C3, has shown promising results as a tumor fibrosis biomarker. However, the fibrotic tumor microenvironment consists of many other collagens with diverse functions and unexplored biomarker potential. One example hereof is type XXII collagen...

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Bibliographic Details
Main Authors: Emilie A. Madsen, Jeppe Thorlacius-Ussing, Neel I. Nissen, Christina Jensen, Inna M. Chen, Julia S. Johansen, Hadi M. H. Diab, Lars N. Jørgensen, Carsten P. Hansen, Morten A. Karsdal, Nicholas Willumsen
Format: Article
Language:English
Published: MDPI AG 2022-11-01
Series:Cells
Subjects:
collagens
ECM
non-invasive biomarker
PDAC
tumor fibrosis
type XXII collagen
Online Access:https://www.mdpi.com/2073-4409/11/23/3763

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