A decline in p38 MAPK signaling underlies immunosenescence in Caenorhabditis elegans.

A decline in p38 MAPK signaling underlies immunosenescence in Caenorhabditis elegans.

The decline in immune function with aging, known as immunosenescence, has been implicated in evolutionarily diverse species, but the underlying molecular mechanisms are not understood. During aging in Caenorhabditis elegans, intestinal tissue deterioration and the increased intestinal proliferation...

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Bibliographic Details
Main Authors: Matthew J Youngman, Zoë N Rogers, Dennis H Kim
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-05-01
Series:PLoS Genetics
Online Access:http://europepmc.org/articles/PMC3098197?pdf=render

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