Osteogenic Potential of Sheep Mesenchymal Stem Cells Preconditioned with BMP-2 and FGF-2 and Seeded on an nHAP-Coated PCL/HAP/β-TCP Scaffold

Osteogenic Potential of Sheep Mesenchymal Stem Cells Preconditioned with BMP-2 and FGF-2 and Seeded on an nHAP-Coated PCL/HAP/β-TCP Scaffold

Mesenchymal stem cells (MSCs) attract interest in regenerative medicine for their potential application in bone regeneration. However, direct transplantation of cells into damaged tissue is not efficient enough to regenerate large bone defects. This problem could be solved with a biocompatible scaff...

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Bibliographic Details
Main Authors: Sandra Stamnitz, Agnieszka Krawczenko, Urszula Szałaj, Żaneta Górecka, Agnieszka Antończyk, Zdzisław Kiełbowicz, Wojciech Święszkowski, Witold Łojkowski, Aleksandra Klimczak
Format: Article
Language:English
Published: MDPI AG 2022-10-01
Series:Cells
Subjects:
mesenchymal stem cells
scaffold
tissue engineering construct
bone regeneration
Online Access:https://www.mdpi.com/2073-4409/11/21/3446

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