Nutritional Characterization, Antioxidant, and Lipid-Lowering Effects of Yellow Mombin (<i>Spondias mombin</i>) Supplemented to Rats Fed a High-Fat Diet
The aim of this study was to evaluate the effects of supplementing yellow mombin (YM) on the oxidative, somatic, and lipid parameters in rats fed a high-fat diet. A total of 24 adult Wistar rats were randomized into three groups: normal-fat diet (NF), high-fat diet (HF), and high-fat diet with YM su...
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| Format: | Article |
| Language: | English |
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MDPI AG
2022-10-01
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| Series: | Foods |
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| Online Access: | https://www.mdpi.com/2304-8158/11/19/3064 |
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| author | Tatiana Luiza Costa Lucena Kamila Sabino Batista Rafael Oliveira Pinheiro Hassler Clementino Cavalcante Jéssyca Alencar de Sousa Gomes Laiane Alves da Silva Priscilla Paulo Lins Fabrícia Souza Ferreira Rafael Ferreira Lima Marcos dos Santos Lima Jailane de Souza Aquino |
| author_facet | Tatiana Luiza Costa Lucena Kamila Sabino Batista Rafael Oliveira Pinheiro Hassler Clementino Cavalcante Jéssyca Alencar de Sousa Gomes Laiane Alves da Silva Priscilla Paulo Lins Fabrícia Souza Ferreira Rafael Ferreira Lima Marcos dos Santos Lima Jailane de Souza Aquino |
| author_sort | Tatiana Luiza Costa Lucena |
| collection | DOAJ |
| description | The aim of this study was to evaluate the effects of supplementing yellow mombin (YM) on the oxidative, somatic, and lipid parameters in rats fed a high-fat diet. A total of 24 adult Wistar rats were randomized into three groups: normal-fat diet (NF), high-fat diet (HF), and high-fat diet with YM supplementation (HFYM). Diets were administered for four weeks, and YM (400 mg/kg) was supplemented via gavage in the last two weeks of the experiment. After the four-week period, the somatic, serum biochemical, and liver oxidative parameters were evaluated. YM has a high antioxidant activity and significant amounts of phenolic compounds, carotenoids, vitamin C, dietary fibre, and minerals. The HFYM group had the lowest body weight (18.75%), body mass index (17.74%), and adiposity (31.63%) compared with the HF group. YM supplementation reduced low-density lipoprotein by 43.05% and increased high-density lipoprotein by 25.73%, but did not improve the triglyceride levels in the serum. YM treatment improved glucose tolerance and lipid peroxidation, and also enhanced the antioxidant capacity, superoxide dismutase, and glutathione peroxidase activities in the liver. These results indicate the lipid-lowering property and potential antioxidant activity of YM against liver oxidative damage caused by a high-fat diet intake, which may be associated with the bioactive compounds present in this fruit. |
| first_indexed | 2024-03-09T21:43:56Z |
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| institution | Directory Open Access Journal |
| issn | 2304-8158 |
| language | English |
| last_indexed | 2024-03-09T21:43:56Z |
| publishDate | 2022-10-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Foods |
| spelling | doaj.art-46ad85dd5c7b4f4e955757ac24d49e5a2023-11-23T20:21:33ZengMDPI AGFoods2304-81582022-10-011119306410.3390/foods11193064Nutritional Characterization, Antioxidant, and Lipid-Lowering Effects of Yellow Mombin (<i>Spondias mombin</i>) Supplemented to Rats Fed a High-Fat DietTatiana Luiza Costa Lucena0Kamila Sabino Batista1Rafael Oliveira Pinheiro2Hassler Clementino Cavalcante3Jéssyca Alencar de Sousa Gomes4Laiane Alves da Silva5Priscilla Paulo Lins6Fabrícia Souza Ferreira7Rafael Ferreira Lima8Marcos dos Santos Lima9Jailane de Souza Aquino10Experimental Nutrition Laboratory—LANEX, Department of Nutrition, Federal University of Paraíba (UFPB), Campus I, João Pessoa 58051-900, Paraíba, BrazilExperimental Nutrition Laboratory—LANEX, Department of Nutrition, Federal University of Paraíba (UFPB), Campus I, João Pessoa 58051-900, Paraíba, BrazilExperimental Nutrition Laboratory—LANEX, Department of Nutrition, Federal University of Paraíba (UFPB), Campus I, João Pessoa 58051-900, Paraíba, BrazilExperimental Nutrition Laboratory—LANEX, Department of Nutrition, Federal University of Paraíba (UFPB), Campus I, João Pessoa 58051-900, Paraíba, BrazilExperimental Nutrition Laboratory—LANEX, Department of Nutrition, Federal University of Paraíba (UFPB), Campus I, João Pessoa 58051-900, Paraíba, BrazilExperimental Nutrition Laboratory—LANEX, Department of Nutrition, Federal University of Paraíba (UFPB), Campus I, João Pessoa 58051-900, Paraíba, BrazilExperimental Nutrition Laboratory—LANEX, Department of Nutrition, Federal University of Paraíba (UFPB), Campus I, João Pessoa 58051-900, Paraíba, BrazilExperimental Nutrition Laboratory—LANEX, Department of Nutrition, Federal University of Paraíba (UFPB), Campus I, João Pessoa 58051-900, Paraíba, BrazilPostgraduate Program in Agroindustrial Systems, Campus Pombal, Federal University of Campina Grande (UFCG), Pombal 58840-000, Paraíba, BrazilPost Graduate Program in Food Science and Technology, Federal University of Paraíba (UFPB), Campus I, João Pessoa 58051-900, Paraíba, BrazilExperimental Nutrition Laboratory—LANEX, Department of Nutrition, Federal University of Paraíba (UFPB), Campus I, João Pessoa 58051-900, Paraíba, BrazilThe aim of this study was to evaluate the effects of supplementing yellow mombin (YM) on the oxidative, somatic, and lipid parameters in rats fed a high-fat diet. A total of 24 adult Wistar rats were randomized into three groups: normal-fat diet (NF), high-fat diet (HF), and high-fat diet with YM supplementation (HFYM). Diets were administered for four weeks, and YM (400 mg/kg) was supplemented via gavage in the last two weeks of the experiment. After the four-week period, the somatic, serum biochemical, and liver oxidative parameters were evaluated. YM has a high antioxidant activity and significant amounts of phenolic compounds, carotenoids, vitamin C, dietary fibre, and minerals. The HFYM group had the lowest body weight (18.75%), body mass index (17.74%), and adiposity (31.63%) compared with the HF group. YM supplementation reduced low-density lipoprotein by 43.05% and increased high-density lipoprotein by 25.73%, but did not improve the triglyceride levels in the serum. YM treatment improved glucose tolerance and lipid peroxidation, and also enhanced the antioxidant capacity, superoxide dismutase, and glutathione peroxidase activities in the liver. These results indicate the lipid-lowering property and potential antioxidant activity of YM against liver oxidative damage caused by a high-fat diet intake, which may be associated with the bioactive compounds present in this fruit.https://www.mdpi.com/2304-8158/11/19/3064adiposityantioxidant enzymescholesterollipids<i>Spondias mombin</i> |
| spellingShingle | Tatiana Luiza Costa Lucena Kamila Sabino Batista Rafael Oliveira Pinheiro Hassler Clementino Cavalcante Jéssyca Alencar de Sousa Gomes Laiane Alves da Silva Priscilla Paulo Lins Fabrícia Souza Ferreira Rafael Ferreira Lima Marcos dos Santos Lima Jailane de Souza Aquino Nutritional Characterization, Antioxidant, and Lipid-Lowering Effects of Yellow Mombin (<i>Spondias mombin</i>) Supplemented to Rats Fed a High-Fat Diet Foods adiposity antioxidant enzymes cholesterol lipids <i>Spondias mombin</i> |
| title | Nutritional Characterization, Antioxidant, and Lipid-Lowering Effects of Yellow Mombin (<i>Spondias mombin</i>) Supplemented to Rats Fed a High-Fat Diet |
| title_full | Nutritional Characterization, Antioxidant, and Lipid-Lowering Effects of Yellow Mombin (<i>Spondias mombin</i>) Supplemented to Rats Fed a High-Fat Diet |
| title_fullStr | Nutritional Characterization, Antioxidant, and Lipid-Lowering Effects of Yellow Mombin (<i>Spondias mombin</i>) Supplemented to Rats Fed a High-Fat Diet |
| title_full_unstemmed | Nutritional Characterization, Antioxidant, and Lipid-Lowering Effects of Yellow Mombin (<i>Spondias mombin</i>) Supplemented to Rats Fed a High-Fat Diet |
| title_short | Nutritional Characterization, Antioxidant, and Lipid-Lowering Effects of Yellow Mombin (<i>Spondias mombin</i>) Supplemented to Rats Fed a High-Fat Diet |
| title_sort | nutritional characterization antioxidant and lipid lowering effects of yellow mombin i spondias mombin i supplemented to rats fed a high fat diet |
| topic | adiposity antioxidant enzymes cholesterol lipids <i>Spondias mombin</i> |
| url | https://www.mdpi.com/2304-8158/11/19/3064 |
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