The Effect of Bariatric Surgery on Polycystic Ovary Syndrome (PCOS) Symptoms and Related Hormones Improvement in Women with Morbid Obesity
Background: Obesity is associated with developing polycystic ovary syndrome (PCOS). The present study investigated whether weight loss after bariatric surgery could improve symptoms and related hormones in women with morbid obesity.Methods: In a retrospective observational study, 50 women aged 18-40...
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| Format: | Article |
| Language: | English |
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Shiraz University of Medical Sciences
2023-09-01
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| Series: | International Journal of Nutrition Sciences |
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| Online Access: | https://ijns.sums.ac.ir/article_49508_9c4f34f43a69238e811c2bf234974669.pdf |
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| author | Ameneh Abtahian Behzad Rezaei Gholamreza Moradpour Ladan Aghakhani Avkan Aghapoor Seyed Hesamaddin Banihashemi Saeideh Izadi Zahra Mohammadi Neda Haghighat |
| author_facet | Ameneh Abtahian Behzad Rezaei Gholamreza Moradpour Ladan Aghakhani Avkan Aghapoor Seyed Hesamaddin Banihashemi Saeideh Izadi Zahra Mohammadi Neda Haghighat |
| author_sort | Ameneh Abtahian |
| collection | DOAJ |
| description | Background: Obesity is associated with developing polycystic ovary syndrome (PCOS). The present study investigated whether weight loss after bariatric surgery could improve symptoms and related hormones in women with morbid obesity.Methods: In a retrospective observational study, 50 women aged 18-40 years with body mass index (BMI)=42.3 kg/m2 who underwent laparoscopic Roux-en-Y gastric bypass (RYGB) were enrolled. Evaluation of anthropometric data, serum testosterone, luteinizing hormone (LH), follicle-stimulating hormone (FSH), prolactin (PRL), fasting plasmaglucose (FPG), and lipid profile were measured preoperatively and at 1-year follow-upResults: Of 50 women, 32 (64%) women were diagnosed to have PCOS. The mean BMI at 1-year follow-up was 27.05 kg/m2. Hirsutism and irregular menstruation resolved entirely among 68.8% (11/16) and 100% (18/18) at 1-year follow-up. There was a significant decrease in total serum testosterone (2.1±0.2 to 0.9±0.1 ng/mL) and LH (8.5±3.36 to 5.02±2.4 mIU/mL) at 1-year follow-up, whether changes in levels of serum FSH, PRL were not significant.Conclusion: Bariatric surgery was effective in weight loss and improvement of PCOS symptoms and related hormones in women with morbid obesity. Thus, women with PCOS and morbid obesity should be eligible for bariatric surgery. |
| first_indexed | 2024-03-11T21:32:42Z |
| format | Article |
| id | doaj.art-46b0b30d573a4565a2fc7288e338f651 |
| institution | Directory Open Access Journal |
| issn | 2538-1873 2538-2829 |
| language | English |
| last_indexed | 2024-03-11T21:32:42Z |
| publishDate | 2023-09-01 |
| publisher | Shiraz University of Medical Sciences |
| record_format | Article |
| series | International Journal of Nutrition Sciences |
| spelling | doaj.art-46b0b30d573a4565a2fc7288e338f6512023-09-27T07:28:50ZengShiraz University of Medical SciencesInternational Journal of Nutrition Sciences2538-18732538-28292023-09-018314414910.30476/ijns.2023.99503.124649508The Effect of Bariatric Surgery on Polycystic Ovary Syndrome (PCOS) Symptoms and Related Hormones Improvement in Women with Morbid ObesityAmeneh Abtahian0Behzad Rezaei1Gholamreza Moradpour2Ladan Aghakhani3Avkan Aghapoor4Seyed Hesamaddin Banihashemi5Saeideh Izadi6Zahra Mohammadi7Neda Haghighat8Department of Obstetrics and Gynecology, School of Medicine, Shahid Beheshti University Of Medical Sciences, Tehran, IranLaparascopy Research Center, Shiraz University of Medical Sciences, Shiraz, IranLaparascopy Research Center, Shiraz University of Medical Sciences, Shiraz, IranLaparascopy Research Center, Shiraz University of Medical Sciences, Shiraz, IranIranian Hospital Dubai, Iranian Red Crescent Society, Dubai, United Arab EmiratesDepartment of surgery, School of Medicine, Hormozgan University of Medical Sciences, Bandar Abbas, IranLaparascopy Research Center, Shiraz University of Medical Sciences, Shiraz, IranLaparascopy Research Center, Shiraz University of Medical Sciences, Shiraz, IranLaparoscopy Research Center, Shiraz University of medical sciences, Shiraz, IranBackground: Obesity is associated with developing polycystic ovary syndrome (PCOS). The present study investigated whether weight loss after bariatric surgery could improve symptoms and related hormones in women with morbid obesity.Methods: In a retrospective observational study, 50 women aged 18-40 years with body mass index (BMI)=42.3 kg/m2 who underwent laparoscopic Roux-en-Y gastric bypass (RYGB) were enrolled. Evaluation of anthropometric data, serum testosterone, luteinizing hormone (LH), follicle-stimulating hormone (FSH), prolactin (PRL), fasting plasmaglucose (FPG), and lipid profile were measured preoperatively and at 1-year follow-upResults: Of 50 women, 32 (64%) women were diagnosed to have PCOS. The mean BMI at 1-year follow-up was 27.05 kg/m2. Hirsutism and irregular menstruation resolved entirely among 68.8% (11/16) and 100% (18/18) at 1-year follow-up. There was a significant decrease in total serum testosterone (2.1±0.2 to 0.9±0.1 ng/mL) and LH (8.5±3.36 to 5.02±2.4 mIU/mL) at 1-year follow-up, whether changes in levels of serum FSH, PRL were not significant.Conclusion: Bariatric surgery was effective in weight loss and improvement of PCOS symptoms and related hormones in women with morbid obesity. Thus, women with PCOS and morbid obesity should be eligible for bariatric surgery.https://ijns.sums.ac.ir/article_49508_9c4f34f43a69238e811c2bf234974669.pdfpolycystic ovary syndromeobesitybariatric surgeryweight lossiran |
| spellingShingle | Ameneh Abtahian Behzad Rezaei Gholamreza Moradpour Ladan Aghakhani Avkan Aghapoor Seyed Hesamaddin Banihashemi Saeideh Izadi Zahra Mohammadi Neda Haghighat The Effect of Bariatric Surgery on Polycystic Ovary Syndrome (PCOS) Symptoms and Related Hormones Improvement in Women with Morbid Obesity International Journal of Nutrition Sciences polycystic ovary syndrome obesity bariatric surgery weight loss iran |
| title | The Effect of Bariatric Surgery on Polycystic Ovary Syndrome (PCOS) Symptoms and Related Hormones Improvement in Women with Morbid Obesity |
| title_full | The Effect of Bariatric Surgery on Polycystic Ovary Syndrome (PCOS) Symptoms and Related Hormones Improvement in Women with Morbid Obesity |
| title_fullStr | The Effect of Bariatric Surgery on Polycystic Ovary Syndrome (PCOS) Symptoms and Related Hormones Improvement in Women with Morbid Obesity |
| title_full_unstemmed | The Effect of Bariatric Surgery on Polycystic Ovary Syndrome (PCOS) Symptoms and Related Hormones Improvement in Women with Morbid Obesity |
| title_short | The Effect of Bariatric Surgery on Polycystic Ovary Syndrome (PCOS) Symptoms and Related Hormones Improvement in Women with Morbid Obesity |
| title_sort | effect of bariatric surgery on polycystic ovary syndrome pcos symptoms and related hormones improvement in women with morbid obesity |
| topic | polycystic ovary syndrome obesity bariatric surgery weight loss iran |
| url | https://ijns.sums.ac.ir/article_49508_9c4f34f43a69238e811c2bf234974669.pdf |
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