A crustacean vitellogenin-derived peptide as an oocyte-specific delivery vehicle for gene silencing

A crustacean vitellogenin-derived peptide as an oocyte-specific delivery vehicle for gene silencing

Gene silencing by dsRNA is well documented in crustaceans, but RNA interference (RNAi) in developing oocytes is yet to be achieved. The main obstacle to RNAi in the oocytes of oviparous animals derives from their protective layers, including the cytosolic membrane, the vitelline envelope, and a laye...

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Bibliographic Details
Main Authors: Shany Cohen, Mahde Hasan, Noa Frishman, Isam Khalaila
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-03-01
Series:Frontiers in Marine Science
Subjects:
RNAi
dsRNA
gene silencing
receptor
endocytosis
vitellogenin
Online Access:https://www.frontiersin.org/articles/10.3389/fmars.2023.1128524/full

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