Functional performance recovery after individualized nutrition therapy combined with a patient-tailored physical rehabilitation program versus standard physiotherapy in patients with long COVID: a pilot study
Abstract Background Long COVID is suggested to be present in 14 to 43% of COVID 19-survivors. Literature on this new condition states a need for a multidisciplinary approach including physical exercise and nutrition. The aim of the current pilot study is to investigate the feasibility of the propose...
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| Format: | Article |
| Language: | English |
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BMC
2023-09-01
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| Series: | Pilot and Feasibility Studies |
| Subjects: | |
| Online Access: | https://doi.org/10.1186/s40814-023-01392-1 |
| _version_ | 1797453871784656896 |
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| author | Stijn Roggeman Berenice Gabriela Jimenez Garcia Lynn Leemans Joy Demol Janne Geers Ann De Smedt Koen Putman Marc Schiltz David Beckwée Elisabeth De Waele |
| author_facet | Stijn Roggeman Berenice Gabriela Jimenez Garcia Lynn Leemans Joy Demol Janne Geers Ann De Smedt Koen Putman Marc Schiltz David Beckwée Elisabeth De Waele |
| author_sort | Stijn Roggeman |
| collection | DOAJ |
| description | Abstract Background Long COVID is suggested to be present in 14 to 43% of COVID 19-survivors. Literature on this new condition states a need for a multidisciplinary approach including physical exercise and nutrition. The aim of the current pilot study is to investigate the feasibility of the proposed protocol to prepare for a randomized controlled study that addresses the effectiveness of a personalized multimodal treatment compared to standard physiotherapy. Methods This is a protocol of the UNLOCK (Nutrition and LOComotoric rehabilitation in long COVID) study, a pragmatic, single center, randomized controlled pilot trial with two groups. Patients with persisting symptoms related to a SARS-CoV-2 infection will receive either standard physiotherapy or a personalized multimodal treatment for a period of 12 weeks, consisting of individualized physical exercise program combined with individualized nutritional therapy. They will be followed-up at 6, 12, and 18 weeks after randomization. Discussion A multidisciplinary approach for dealing with long COVID is needed. Because of the lack of clear data and the fact that this is a very heterogenic group, we aim to prepare and optimize a randomized controlled study that addresses the effectiveness of a personalized multimodal treatment. Trial registration ClinicalTrials.gov Identifier: NCT05254301 (since February 24, 2022). |
| first_indexed | 2024-03-09T15:28:08Z |
| format | Article |
| id | doaj.art-46b2608ea81a455ca1ce5d0483f61e97 |
| institution | Directory Open Access Journal |
| issn | 2055-5784 |
| language | English |
| last_indexed | 2024-03-09T15:28:08Z |
| publishDate | 2023-09-01 |
| publisher | BMC |
| record_format | Article |
| series | Pilot and Feasibility Studies |
| spelling | doaj.art-46b2608ea81a455ca1ce5d0483f61e972023-11-26T12:22:42ZengBMCPilot and Feasibility Studies2055-57842023-09-01911910.1186/s40814-023-01392-1Functional performance recovery after individualized nutrition therapy combined with a patient-tailored physical rehabilitation program versus standard physiotherapy in patients with long COVID: a pilot studyStijn Roggeman0Berenice Gabriela Jimenez Garcia1Lynn Leemans2Joy Demol3Janne Geers4Ann De Smedt5Koen Putman6Marc Schiltz7David Beckwée8Elisabeth De Waele9Department of Physical Medicine and Rehabilitation, Vrije Universiteit Brussel (VUB), Universitair Ziekenhuis Brussel (UZ Brussel)Department of Clinical Nutrition and Dietetics, Vrije Universiteit Brussel (VUB), Universitair Ziekenhuis Brussel (UZ Brussel)Department of Clinical Nutrition and Dietetics, Vrije Universiteit Brussel (VUB), Universitair Ziekenhuis Brussel (UZ Brussel)Department of Clinical Nutrition and Dietetics, Vrije Universiteit Brussel (VUB), Universitair Ziekenhuis Brussel (UZ Brussel)Department of Clinical Nutrition and Dietetics, Vrije Universiteit Brussel (VUB), Universitair Ziekenhuis Brussel (UZ Brussel)Department of Physical Medicine and Rehabilitation, Vrije Universiteit Brussel (VUB), Universitair Ziekenhuis Brussel (UZ Brussel)Interuniversity Centre for Health Economics Research (I-CHER), Vrije Universiteit Brussel (VUB)Department of Physical Medicine and Rehabilitation, Vrije Universiteit Brussel (VUB), Universitair Ziekenhuis Brussel (UZ Brussel)Research Group Rehabilitation Research (RERE), Vrije Universiteit BrusselDepartment of Clinical Nutrition and Dietetics, Vrije Universiteit Brussel (VUB), Universitair Ziekenhuis Brussel (UZ Brussel)Abstract Background Long COVID is suggested to be present in 14 to 43% of COVID 19-survivors. Literature on this new condition states a need for a multidisciplinary approach including physical exercise and nutrition. The aim of the current pilot study is to investigate the feasibility of the proposed protocol to prepare for a randomized controlled study that addresses the effectiveness of a personalized multimodal treatment compared to standard physiotherapy. Methods This is a protocol of the UNLOCK (Nutrition and LOComotoric rehabilitation in long COVID) study, a pragmatic, single center, randomized controlled pilot trial with two groups. Patients with persisting symptoms related to a SARS-CoV-2 infection will receive either standard physiotherapy or a personalized multimodal treatment for a period of 12 weeks, consisting of individualized physical exercise program combined with individualized nutritional therapy. They will be followed-up at 6, 12, and 18 weeks after randomization. Discussion A multidisciplinary approach for dealing with long COVID is needed. Because of the lack of clear data and the fact that this is a very heterogenic group, we aim to prepare and optimize a randomized controlled study that addresses the effectiveness of a personalized multimodal treatment. Trial registration ClinicalTrials.gov Identifier: NCT05254301 (since February 24, 2022).https://doi.org/10.1186/s40814-023-01392-1Long COVIDPhysical exerciseNutritionRehabilitation |
| spellingShingle | Stijn Roggeman Berenice Gabriela Jimenez Garcia Lynn Leemans Joy Demol Janne Geers Ann De Smedt Koen Putman Marc Schiltz David Beckwée Elisabeth De Waele Functional performance recovery after individualized nutrition therapy combined with a patient-tailored physical rehabilitation program versus standard physiotherapy in patients with long COVID: a pilot study Pilot and Feasibility Studies Long COVID Physical exercise Nutrition Rehabilitation |
| title | Functional performance recovery after individualized nutrition therapy combined with a patient-tailored physical rehabilitation program versus standard physiotherapy in patients with long COVID: a pilot study |
| title_full | Functional performance recovery after individualized nutrition therapy combined with a patient-tailored physical rehabilitation program versus standard physiotherapy in patients with long COVID: a pilot study |
| title_fullStr | Functional performance recovery after individualized nutrition therapy combined with a patient-tailored physical rehabilitation program versus standard physiotherapy in patients with long COVID: a pilot study |
| title_full_unstemmed | Functional performance recovery after individualized nutrition therapy combined with a patient-tailored physical rehabilitation program versus standard physiotherapy in patients with long COVID: a pilot study |
| title_short | Functional performance recovery after individualized nutrition therapy combined with a patient-tailored physical rehabilitation program versus standard physiotherapy in patients with long COVID: a pilot study |
| title_sort | functional performance recovery after individualized nutrition therapy combined with a patient tailored physical rehabilitation program versus standard physiotherapy in patients with long covid a pilot study |
| topic | Long COVID Physical exercise Nutrition Rehabilitation |
| url | https://doi.org/10.1186/s40814-023-01392-1 |
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