Synthesis and Biological Evaluation of Novel Benzothiazole Derivatives as Potential Anticonvulsant Agents

New benztriazoles with a mercapto-triazole and other heterocycle substituents were synthesized and evaluated for their anticonvulsant activity and neurotoxicity by using the maximal electroshock (MES), subcutaneous pentylenetetrazole (scPTZ), and rotarod neurotoxicity (TOX) tests. Among the compound...

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Main Authors: Da-Chuan Liu, Hong-Jian Zhang, Chun-Mei Jin, Zhe-Shan Quan
格式: Article
語言:English
出版: MDPI AG 2016-02-01
叢編:Molecules
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在線閱讀:http://www.mdpi.com/1420-3049/21/3/164