Synthesis and Biological Evaluation of Novel Benzothiazole Derivatives as Potential Anticonvulsant Agents

New benztriazoles with a mercapto-triazole and other heterocycle substituents were synthesized and evaluated for their anticonvulsant activity and neurotoxicity by using the maximal electroshock (MES), subcutaneous pentylenetetrazole (scPTZ), and rotarod neurotoxicity (TOX) tests. Among the compound...

Ausführliche Beschreibung

Bibliographische Detailangaben
Hauptverfasser: Da-Chuan Liu, Hong-Jian Zhang, Chun-Mei Jin, Zhe-Shan Quan
Format: Artikel
Sprache:English
Veröffentlicht: MDPI AG 2016-02-01
Schriftenreihe:Molecules
Schlagworte:
Online Zugang:http://www.mdpi.com/1420-3049/21/3/164