Diagnostic relevance of fine needle aspiration cytology in nodular thyroid lesions
Background/Aim. Fine needle aspiration cytology (FNAC) of the thyroid gland has been used as an initial investigative procedure of thyroid nodule(s) in the Department of Pathology at the Institute of Oncology of Vojvodina for more than 20 years. This procedure is rapid, inexpensive and technologi...
| Main Authors: | , , , , , , , |
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| Format: | Article |
| Language: | English |
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Military Health Department, Ministry of Defance, Serbia
2012-01-01
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| Series: | Vojnosanitetski Pregled |
| Subjects: | |
| Online Access: | http://www.doiserbia.nb.rs/img/doi/0042-8450/2012/0042-84501207555K.pdf |
| _version_ | 1818908670796234752 |
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| author | Knežević-Ušaj Slavica Eri Živka Panjković Milana Klem Ištvan Petrović Tomislav Ivković-Kapicl Tatjana Karapandžić Aleksandra Jelić Jasmina |
| author_facet | Knežević-Ušaj Slavica Eri Živka Panjković Milana Klem Ištvan Petrović Tomislav Ivković-Kapicl Tatjana Karapandžić Aleksandra Jelić Jasmina |
| author_sort | Knežević-Ušaj Slavica |
| collection | DOAJ |
| description | Background/Aim. Fine needle aspiration cytology (FNAC) of the thyroid gland has been used as an initial investigative procedure of thyroid nodule(s) in the Department of Pathology at the Institute of Oncology of Vojvodina for more than 20 years. This procedure is rapid, inexpensive and technologically simple, yet it has found only limited, albeit increasing acceptance in medical practice in Serbia. The aim of the study was to evaluate our FNAC findings by correlating cytological results with histological diagnosis and to define the sensitivity, diagnostic accuracy and positive predictive value of FNAC. Methods. A total of 266 patients with thyroid swellings were aspirated in one year investigated period at our Institute out of whom 69 underwent surgery between May 2008 and May 2009. The cytological results correlated with clinical features, ultrasound investigations (US) and subsequent histopathological examination of the resected tissue. Results. By the use of cytology we found out thyroid carcinoma in 10 patients, and by histopathological examination in 12. We obtained 83% sensitivity, 100% specificity and 97% of diagnostic accuracy of FNAC. Conclusion. The obtained results confirm the importance of FNAC in preoperative assesment of thyroid nodule. |
| first_indexed | 2024-12-19T22:14:43Z |
| format | Article |
| id | doaj.art-46b95e56770d4f06958a45d201216143 |
| institution | Directory Open Access Journal |
| issn | 0042-8450 |
| language | English |
| last_indexed | 2024-12-19T22:14:43Z |
| publishDate | 2012-01-01 |
| publisher | Military Health Department, Ministry of Defance, Serbia |
| record_format | Article |
| series | Vojnosanitetski Pregled |
| spelling | doaj.art-46b95e56770d4f06958a45d2012161432022-12-21T20:03:47ZengMilitary Health Department, Ministry of Defance, SerbiaVojnosanitetski Pregled0042-84502012-01-0169755556110.2298/VSP1207555KDiagnostic relevance of fine needle aspiration cytology in nodular thyroid lesionsKnežević-Ušaj SlavicaEri ŽivkaPanjković MilanaKlem IštvanPetrović TomislavIvković-Kapicl TatjanaKarapandžić AleksandraJelić JasminaBackground/Aim. Fine needle aspiration cytology (FNAC) of the thyroid gland has been used as an initial investigative procedure of thyroid nodule(s) in the Department of Pathology at the Institute of Oncology of Vojvodina for more than 20 years. This procedure is rapid, inexpensive and technologically simple, yet it has found only limited, albeit increasing acceptance in medical practice in Serbia. The aim of the study was to evaluate our FNAC findings by correlating cytological results with histological diagnosis and to define the sensitivity, diagnostic accuracy and positive predictive value of FNAC. Methods. A total of 266 patients with thyroid swellings were aspirated in one year investigated period at our Institute out of whom 69 underwent surgery between May 2008 and May 2009. The cytological results correlated with clinical features, ultrasound investigations (US) and subsequent histopathological examination of the resected tissue. Results. By the use of cytology we found out thyroid carcinoma in 10 patients, and by histopathological examination in 12. We obtained 83% sensitivity, 100% specificity and 97% of diagnostic accuracy of FNAC. Conclusion. The obtained results confirm the importance of FNAC in preoperative assesment of thyroid nodule.http://www.doiserbia.nb.rs/img/doi/0042-8450/2012/0042-84501207555K.pdfgoiter, nodularcytological techniquesbiopsy, fine-needlehistologysensitivity and specificity |
| spellingShingle | Knežević-Ušaj Slavica Eri Živka Panjković Milana Klem Ištvan Petrović Tomislav Ivković-Kapicl Tatjana Karapandžić Aleksandra Jelić Jasmina Diagnostic relevance of fine needle aspiration cytology in nodular thyroid lesions Vojnosanitetski Pregled goiter, nodular cytological techniques biopsy, fine-needle histology sensitivity and specificity |
| title | Diagnostic relevance of fine needle aspiration cytology in nodular thyroid lesions |
| title_full | Diagnostic relevance of fine needle aspiration cytology in nodular thyroid lesions |
| title_fullStr | Diagnostic relevance of fine needle aspiration cytology in nodular thyroid lesions |
| title_full_unstemmed | Diagnostic relevance of fine needle aspiration cytology in nodular thyroid lesions |
| title_short | Diagnostic relevance of fine needle aspiration cytology in nodular thyroid lesions |
| title_sort | diagnostic relevance of fine needle aspiration cytology in nodular thyroid lesions |
| topic | goiter, nodular cytological techniques biopsy, fine-needle histology sensitivity and specificity |
| url | http://www.doiserbia.nb.rs/img/doi/0042-8450/2012/0042-84501207555K.pdf |
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