Genome‐Wide Associations of Global Electrical Heterogeneity ECG Phenotype: The ARIC (Atherosclerosis Risk in Communities) Study and CHS (Cardiovascular Health Study)

Genome‐Wide Associations of Global Electrical Heterogeneity ECG Phenotype: The ARIC (Atherosclerosis Risk in Communities) Study and CHS (Cardiovascular Health Study)

BackgroundECG global electrical heterogeneity (GEH) is associated with sudden cardiac death. We hypothesized that a genome‐wide association study would identify genetic loci related to GEH. Methods and ResultsWe tested genotyped and imputed variants in black (N=3057) and white (N=10 769) participant...

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Bibliographic Details
Main Authors: Larisa G. Tereshchenko, Nona Sotoodehnia, Colleen M. Sitlani, Foram N. Ashar, Muammar Kabir, Mary L. Biggs, Michael P. Morley, Jonathan W. Waks, Elsayed Z. Soliman, Alfred E. Buxton, Tor Biering‐Sørensen, Scott D. Solomon, Wendy S. Post, Thomas P. Cappola, David S. Siscovick, Dan E. Arking
Format: Article
Language:English
Published: Wiley 2018-04-01
Series:Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Subjects:
ECG
electrocardiography
genome wide association study
global electrical heterogeneity
spatial ventricular gradient
sum absolute QRST integral
Online Access:https://www.ahajournals.org/doi/10.1161/JAHA.117.008160

Internet

https://www.ahajournals.org/doi/10.1161/JAHA.117.008160

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