Low vitamin D levels in post-menopausal women are associated with complex regional pain syndrome type I in surgically treated distal radius fractures
Abstract Background Complex regional pain syndrome type I (CRPS I) is a chronic devastating condition and a relatively common complication of distal radius fractures (DRF). The purpose of this study was to investigate the relationship of vitamin D levels in surgically treated post-menopausal women w...
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| Format: | Article |
| Language: | English |
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BMC
2020-08-01
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| Series: | Journal of Orthopaedic Surgery and Research |
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| Online Access: | http://link.springer.com/article/10.1186/s13018-020-01859-4 |
| _version_ | 1817993055438897152 |
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| author | Sang-Uk Lee Ki-Tae Na Yoon-Min Lee Jong Hwa Park Sun Young Joo |
| author_facet | Sang-Uk Lee Ki-Tae Na Yoon-Min Lee Jong Hwa Park Sun Young Joo |
| author_sort | Sang-Uk Lee |
| collection | DOAJ |
| description | Abstract Background Complex regional pain syndrome type I (CRPS I) is a chronic devastating condition and a relatively common complication of distal radius fractures (DRF). The purpose of this study was to investigate the relationship of vitamin D levels in surgically treated post-menopausal women with CRPS I occurrence in DRF. Methods From February 2016 to March 2017, 158 surgically treated post-menopausal patients with DRF were enrolled. Exclusion criteria were (1) patients who had been taking vitamin D or osteoporosis medication at the time of injury; (2) patients with medical factors that may affect vitamin D levels; (3) patients who were reluctant to enroll in the study; and (4) patient with additional fractures, ligamentous injuries, or neuropathy. A total of 107 patients were available for final analysis. We compared the serum vitamin D levels in post-menopausal women with DRF with CRPS I (group 1) and without CRPS I (group 2). Bone mineral density (BMD) of the femur and spine, osteocalcin, alkaline phosphatase (ALP), body mass index (BMI) were also measured. Results The average age at the time of surgery was 66.5 years (range, 39-86 years). The mean follow-up period was 16.3 months after surgery. Among the 107 surgically treated DRF patients, 19 (18%) met the Budapest criteria for CRPS I during the follow-up period. The mean serum vitamin D level in group 1 (15.2 ng/ml) was significantly lower than that in group 2 (20.5 ng/ml, p = 0.027). The mean values of osteocalcin, ALP, BMI, and BMD were not significantly different between the groups. Conclusion Lower vitamin D levels in post-menopausal women can increase CRPS I occurrence in distal radius fractures. |
| first_indexed | 2024-04-14T01:34:40Z |
| format | Article |
| id | doaj.art-46bae3f22df8462190835bddf5538281 |
| institution | Directory Open Access Journal |
| issn | 1749-799X |
| language | English |
| last_indexed | 2024-04-14T01:34:40Z |
| publishDate | 2020-08-01 |
| publisher | BMC |
| record_format | Article |
| series | Journal of Orthopaedic Surgery and Research |
| spelling | doaj.art-46bae3f22df8462190835bddf55382812022-12-22T02:20:02ZengBMCJournal of Orthopaedic Surgery and Research1749-799X2020-08-011511710.1186/s13018-020-01859-4Low vitamin D levels in post-menopausal women are associated with complex regional pain syndrome type I in surgically treated distal radius fracturesSang-Uk Lee0Ki-Tae Na1Yoon-Min Lee2Jong Hwa Park3Sun Young Joo4Department of Orthopedic Surgery, Incheon St. Mary’s Hospital, The Catholic University of KoreaDepartment of Orthopedic Surgery, Incheon St. Mary’s Hospital, The Catholic University of KoreaDepartment of Orthopedic Surgery, Yeouido St. Mary’s Hospital, The Catholic University of KoreaDepartment of Orthopedic Surgery, Incheon St. Mary’s Hospital, The Catholic University of KoreaDepartment of Orthopedic Surgery, Incheon St. Mary’s Hospital, The Catholic University of KoreaAbstract Background Complex regional pain syndrome type I (CRPS I) is a chronic devastating condition and a relatively common complication of distal radius fractures (DRF). The purpose of this study was to investigate the relationship of vitamin D levels in surgically treated post-menopausal women with CRPS I occurrence in DRF. Methods From February 2016 to March 2017, 158 surgically treated post-menopausal patients with DRF were enrolled. Exclusion criteria were (1) patients who had been taking vitamin D or osteoporosis medication at the time of injury; (2) patients with medical factors that may affect vitamin D levels; (3) patients who were reluctant to enroll in the study; and (4) patient with additional fractures, ligamentous injuries, or neuropathy. A total of 107 patients were available for final analysis. We compared the serum vitamin D levels in post-menopausal women with DRF with CRPS I (group 1) and without CRPS I (group 2). Bone mineral density (BMD) of the femur and spine, osteocalcin, alkaline phosphatase (ALP), body mass index (BMI) were also measured. Results The average age at the time of surgery was 66.5 years (range, 39-86 years). The mean follow-up period was 16.3 months after surgery. Among the 107 surgically treated DRF patients, 19 (18%) met the Budapest criteria for CRPS I during the follow-up period. The mean serum vitamin D level in group 1 (15.2 ng/ml) was significantly lower than that in group 2 (20.5 ng/ml, p = 0.027). The mean values of osteocalcin, ALP, BMI, and BMD were not significantly different between the groups. Conclusion Lower vitamin D levels in post-menopausal women can increase CRPS I occurrence in distal radius fractures.http://link.springer.com/article/10.1186/s13018-020-01859-4Vitamin DComplex regional pain syndromeDistal radius fracture |
| spellingShingle | Sang-Uk Lee Ki-Tae Na Yoon-Min Lee Jong Hwa Park Sun Young Joo Low vitamin D levels in post-menopausal women are associated with complex regional pain syndrome type I in surgically treated distal radius fractures Journal of Orthopaedic Surgery and Research Vitamin D Complex regional pain syndrome Distal radius fracture |
| title | Low vitamin D levels in post-menopausal women are associated with complex regional pain syndrome type I in surgically treated distal radius fractures |
| title_full | Low vitamin D levels in post-menopausal women are associated with complex regional pain syndrome type I in surgically treated distal radius fractures |
| title_fullStr | Low vitamin D levels in post-menopausal women are associated with complex regional pain syndrome type I in surgically treated distal radius fractures |
| title_full_unstemmed | Low vitamin D levels in post-menopausal women are associated with complex regional pain syndrome type I in surgically treated distal radius fractures |
| title_short | Low vitamin D levels in post-menopausal women are associated with complex regional pain syndrome type I in surgically treated distal radius fractures |
| title_sort | low vitamin d levels in post menopausal women are associated with complex regional pain syndrome type i in surgically treated distal radius fractures |
| topic | Vitamin D Complex regional pain syndrome Distal radius fracture |
| url | http://link.springer.com/article/10.1186/s13018-020-01859-4 |
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