Evaluation of two statistical methods provides insights into the complex patterns of alternative polyadenylation site switching.

Evaluation of two statistical methods provides insights into the complex patterns of alternative polyadenylation site switching.

Switching between different alternative polyadenylation (APA) sites plays an important role in the fine tuning of gene expression. New technologies for the execution of 3'-end enriched RNA-seq allow genome-wide detection of the genes that exhibit significant APA site switching between different...

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Bibliographic Details
Main Authors: Jie Li, Rui Li, Leiming You, Anlong Xu, Yonggui Fu, Shengfeng Huang
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4396989?pdf=render

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