Human seminal plasma stimulates the migration of CD11c+ mononuclear phagocytes to the apical side of the colonic epithelium without altering the junctional complexes in an ex vivo human intestinal model

Human seminal plasma stimulates the migration of CD11c+ mononuclear phagocytes to the apical side of the colonic epithelium without altering the junctional complexes in an ex vivo human intestinal model

IntroductionHuman immunodeficiency virus type 1 (HIV) transmission mostly occurs through the genital and intestinal mucosae. Although HIV-1 transmission has been extensively investigated, gaps remain in understanding the initial steps of HIV entry through the colonic mucosa. We previously showed tha...

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Bibliographic Details
Main Authors: Marco Baratella, Valeria Iannone, Mariangela Cavarelli, Chiara Foglieni, Paola Viganò, Christiane Moog, Ugo Elmore, Silvia Nozza, Massimo Alfano, Andrea Salonia, Stefania Dispinseri, Gabriella Scarlatti
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-03-01
Series:Frontiers in Immunology
Subjects:
HIV-1 transmission
intestinal mucosa
human seminal plasma
mononuclear phagocytes
CD11c+ cells migration
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2023.1133886/full

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