Early Growth Response Gene 2-Expressing CD4+LAG3+ Regulatory T Cells: The Therapeutic Potential for Treating Autoimmune Diseases

Early Growth Response Gene 2-Expressing CD4+LAG3+ Regulatory T Cells: The Therapeutic Potential for Treating Autoimmune Diseases

Regulatory T cells (Tregs) are necessary for the maintenance of immune tolerance. Tregs are divided into two major populations: one is thymus derived and the other develops in the periphery. Among these Tregs, CD4+CD25+ Tregs, which mainly originate in the thymus, have been extensively studied. Tran...

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Bibliografiske detaljer
Main Authors: Tomohisa Okamura, Kazuhiko Yamamoto, Keishi Fujio
Format: Article
Sprog:English
Udgivet: Frontiers Media S.A. 2018-02-01
Serier:Frontiers in Immunology
Fag:
Egr2
Egr3
lymphocyte activation gene 3
Foxp3
regulatory T cell
gene therapy
Online adgang:http://journal.frontiersin.org/article/10.3389/fimmu.2018.00340/full

Internet

http://journal.frontiersin.org/article/10.3389/fimmu.2018.00340/full

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