Early Growth Response Gene 2-Expressing CD4+LAG3+ Regulatory T Cells: The Therapeutic Potential for Treating Autoimmune Diseases

Regulatory T cells (Tregs) are necessary for the maintenance of immune tolerance. Tregs are divided into two major populations: one is thymus derived and the other develops in the periphery. Among these Tregs, CD4+CD25+ Tregs, which mainly originate in the thymus, have been extensively studied. Tran...

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Hlavní autoři: Tomohisa Okamura, Kazuhiko Yamamoto, Keishi Fujio
Médium: Článek
Jazyk:English
Vydáno: Frontiers Media S.A. 2018-02-01
Edice:Frontiers in Immunology
Témata:
On-line přístup:http://journal.frontiersin.org/article/10.3389/fimmu.2018.00340/full