Cholecystitis after Placement of Covered Self-Expandable Metallic Stents in Patients with Distal Malignant Biliary Obstructions
Background/Aims Cholecystitis can occur after the placement of covered self-expandable metallic stents for distal malignant biliary obstructions. We aimed to identify risk factors for cholecystitis following covered self-expandable metallic stent placement. Methods We investigated risk factors relat...
| Main Authors: | , , , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
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Korean Society of Gastrointestinal Endoscopy
2021-07-01
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| Series: | Clinical Endoscopy |
| Subjects: | |
| Online Access: | http://www.e-ce.org/upload/pdf/ce-2020-136.pdf |
| _version_ | 1827615147799085056 |
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| author | Masafumi Watanabe Kosuke Okuwaki Jun Woo Mitsuhiro Kida Hiroshi Imaizumi Tomohisa Iwai Hiroshi Yamauchi Toru Kaneko Rikiya Hasegawa Takahiro Kurosu Naoki Minato Hiroki Haradome Wasaburo Koizumi |
| author_facet | Masafumi Watanabe Kosuke Okuwaki Jun Woo Mitsuhiro Kida Hiroshi Imaizumi Tomohisa Iwai Hiroshi Yamauchi Toru Kaneko Rikiya Hasegawa Takahiro Kurosu Naoki Minato Hiroki Haradome Wasaburo Koizumi |
| author_sort | Masafumi Watanabe |
| collection | DOAJ |
| description | Background/Aims Cholecystitis can occur after the placement of covered self-expandable metallic stents for distal malignant biliary obstructions. We aimed to identify risk factors for cholecystitis following covered self-expandable metallic stent placement. Methods We investigated risk factors related to cholecystitis following covered self-expandable metallic stent placement in 118 patients with distal malignant biliary obstructions between January 1, 2015 and April 30, 2019. Endoscopic assessments and tumor invasion to the arteries feeding the gallbladder were determined by a pancreaticobiliary endoscopist and a radiologist, respectively. Results The median patient age was 72 years (men, 61.0%). The flow of the contrast agent into the gallbladder and tumor involvement in the orifice of the cystic duct were observed in 35 (29.7%) and 35 (29.7%) patients, respectively. During the observation period (median, 179 days), cholecystitis occurred in 18 (15.3%) patients. Multivariate analysis revealed the flow of the contrast agent into the gallbladder (p=0.023) and tumor involvement in the orifice of the cystic duct (p=0.005) as significant independent risk factors associated with cholecystitis. Conclusions The flow of the contrast agent into the gallbladder and tumor involvement in the orifice of the cystic duct are potential independent risk factors for cholecystitis following the placement of covered self-expandable metallic stents. A follow-up prospective study is warranted to validate their influence. |
| first_indexed | 2024-03-09T09:06:56Z |
| format | Article |
| id | doaj.art-46ccfb10a21a4ffb84f963b489e03f37 |
| institution | Directory Open Access Journal |
| issn | 2234-2400 2234-2443 |
| language | English |
| last_indexed | 2024-03-09T09:06:56Z |
| publishDate | 2021-07-01 |
| publisher | Korean Society of Gastrointestinal Endoscopy |
| record_format | Article |
| series | Clinical Endoscopy |
| spelling | doaj.art-46ccfb10a21a4ffb84f963b489e03f372023-12-02T10:11:04ZengKorean Society of Gastrointestinal EndoscopyClinical Endoscopy2234-24002234-24432021-07-0154458959510.5946/ce.2020.1367429Cholecystitis after Placement of Covered Self-Expandable Metallic Stents in Patients with Distal Malignant Biliary ObstructionsMasafumi Watanabe0Kosuke Okuwaki1Jun Woo2Mitsuhiro Kida3Hiroshi Imaizumi4Tomohisa Iwai5Hiroshi Yamauchi6Toru Kaneko7Rikiya Hasegawa8Takahiro Kurosu9Naoki Minato10Hiroki Haradome11Wasaburo Koizumi12 Department of Gastroenterology, Kitasato University School of Medicine, Sagamihara, Kanagawa, Japan Department of Gastroenterology, Kitasato University School of Medicine, Sagamihara, Kanagawa, Japan Department of Diagnostic Radiology, Kitasato University School of Medicine, Sagamihara, Kanagawa, Japan Department of Gastroenterology, Kitasato University School of Medicine, Sagamihara, Kanagawa, Japan Department of Gastroenterology, Kitasato University School of Medicine, Sagamihara, Kanagawa, Japan Department of Gastroenterology, Kitasato University School of Medicine, Sagamihara, Kanagawa, Japan Department of Gastroenterology, Kitasato University School of Medicine, Sagamihara, Kanagawa, Japan Department of Gastroenterology, Kitasato University School of Medicine, Sagamihara, Kanagawa, Japan Department of Gastroenterology, Kitasato University School of Medicine, Sagamihara, Kanagawa, Japan Department of Gastroenterology, Kitasato University School of Medicine, Sagamihara, Kanagawa, Japan Department of Gastroenterology, Kitasato University School of Medicine, Sagamihara, Kanagawa, Japan Department of Radiological Advanced Medicine, Kitasato University School of Medicine, Sagamihara, Kanagawa, Japan Department of Gastroenterology, Kitasato University School of Medicine, Sagamihara, Kanagawa, JapanBackground/Aims Cholecystitis can occur after the placement of covered self-expandable metallic stents for distal malignant biliary obstructions. We aimed to identify risk factors for cholecystitis following covered self-expandable metallic stent placement. Methods We investigated risk factors related to cholecystitis following covered self-expandable metallic stent placement in 118 patients with distal malignant biliary obstructions between January 1, 2015 and April 30, 2019. Endoscopic assessments and tumor invasion to the arteries feeding the gallbladder were determined by a pancreaticobiliary endoscopist and a radiologist, respectively. Results The median patient age was 72 years (men, 61.0%). The flow of the contrast agent into the gallbladder and tumor involvement in the orifice of the cystic duct were observed in 35 (29.7%) and 35 (29.7%) patients, respectively. During the observation period (median, 179 days), cholecystitis occurred in 18 (15.3%) patients. Multivariate analysis revealed the flow of the contrast agent into the gallbladder (p=0.023) and tumor involvement in the orifice of the cystic duct (p=0.005) as significant independent risk factors associated with cholecystitis. Conclusions The flow of the contrast agent into the gallbladder and tumor involvement in the orifice of the cystic duct are potential independent risk factors for cholecystitis following the placement of covered self-expandable metallic stents. A follow-up prospective study is warranted to validate their influence.http://www.e-ce.org/upload/pdf/ce-2020-136.pdfcholecystitisendoscopic retrograde cholangiopancreatographymalignant biliary obstructionrisk factorsself-expandable metallic stents |
| spellingShingle | Masafumi Watanabe Kosuke Okuwaki Jun Woo Mitsuhiro Kida Hiroshi Imaizumi Tomohisa Iwai Hiroshi Yamauchi Toru Kaneko Rikiya Hasegawa Takahiro Kurosu Naoki Minato Hiroki Haradome Wasaburo Koizumi Cholecystitis after Placement of Covered Self-Expandable Metallic Stents in Patients with Distal Malignant Biliary Obstructions Clinical Endoscopy cholecystitis endoscopic retrograde cholangiopancreatography malignant biliary obstruction risk factors self-expandable metallic stents |
| title | Cholecystitis after Placement of Covered Self-Expandable Metallic Stents in Patients with Distal Malignant Biliary Obstructions |
| title_full | Cholecystitis after Placement of Covered Self-Expandable Metallic Stents in Patients with Distal Malignant Biliary Obstructions |
| title_fullStr | Cholecystitis after Placement of Covered Self-Expandable Metallic Stents in Patients with Distal Malignant Biliary Obstructions |
| title_full_unstemmed | Cholecystitis after Placement of Covered Self-Expandable Metallic Stents in Patients with Distal Malignant Biliary Obstructions |
| title_short | Cholecystitis after Placement of Covered Self-Expandable Metallic Stents in Patients with Distal Malignant Biliary Obstructions |
| title_sort | cholecystitis after placement of covered self expandable metallic stents in patients with distal malignant biliary obstructions |
| topic | cholecystitis endoscopic retrograde cholangiopancreatography malignant biliary obstruction risk factors self-expandable metallic stents |
| url | http://www.e-ce.org/upload/pdf/ce-2020-136.pdf |
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