Synthesis, NMR, DFT and antimicrobial studies of Zn(II) complexes with N-benzyloxycarbonyl-S-alanine
In this study, the first complexes of Zn(II) with the N-benzyloxycar- bonyl-S-alaninato ligand (N-Boc-S-ala) were synthesized. The new complexes were characterized by elemental analysis, conductometric measurements, IR, 1H-NMR, 13C-NMR and 2D-NMR spectroscopy. On the basis of the experimental data,...
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| Format: | Article |
| Language: | English |
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Serbian Chemical Society
2008-01-01
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| Series: | Journal of the Serbian Chemical Society |
| Subjects: | |
| Online Access: | http://www.doiserbia.nb.rs/img/doi/0352-5139/2008/0352-51390809815M.pdf |
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| author | Mitić Dragana M. Miodragović Đenana U. Sladić Dušan M. Vitnik Željko J. Miodragović Zoran M. Anđelković Katarina K. Radulović Milanka Đ. Juranić Nenad O. |
| author_facet | Mitić Dragana M. Miodragović Đenana U. Sladić Dušan M. Vitnik Željko J. Miodragović Zoran M. Anđelković Katarina K. Radulović Milanka Đ. Juranić Nenad O. |
| author_sort | Mitić Dragana M. |
| collection | DOAJ |
| description | In this study, the first complexes of Zn(II) with the N-benzyloxycar- bonyl-S-alaninato ligand (N-Boc-S-ala) were synthesized. The new complexes were characterized by elemental analysis, conductometric measurements, IR, 1H-NMR, 13C-NMR and 2D-NMR spectroscopy. On the basis of the experimental data, tetrahedral geometry of the Zn(II) complexes was proposed. A very good agreement between the NMR and DFT calculated data was obtained. Investigation of antimicrobial activity of the newly synthesized complexes was also performed. It was established that [Zn(N-Boc-S-ala)2] was selective and acts only on Candida albicans. |
| first_indexed | 2024-12-19T16:12:14Z |
| format | Article |
| id | doaj.art-46cfb500ea644e0f8e781157badae727 |
| institution | Directory Open Access Journal |
| issn | 0352-5139 1820-7421 |
| language | English |
| last_indexed | 2024-12-19T16:12:14Z |
| publishDate | 2008-01-01 |
| publisher | Serbian Chemical Society |
| record_format | Article |
| series | Journal of the Serbian Chemical Society |
| spelling | doaj.art-46cfb500ea644e0f8e781157badae7272022-12-21T20:14:43ZengSerbian Chemical SocietyJournal of the Serbian Chemical Society0352-51391820-74212008-01-01738-981582410.2298/JSC0809815M0352-51390809815MSynthesis, NMR, DFT and antimicrobial studies of Zn(II) complexes with N-benzyloxycarbonyl-S-alanineMitić Dragana M.0Miodragović Đenana U.1Sladić Dušan M.2Vitnik Željko J.3Miodragović Zoran M.4Anđelković Katarina K.5Radulović Milanka Đ.6Juranić Nenad O.7Hemijski fakultet, BeogradHemijski fakultet, BeogradHemijski fakultet, BeogradHemijski fakultet, BeogradHemijski fakultet, BeogradHemijski fakultet, BeogradCentar za hemiju, Institut za hemiju, tehnologiju i metalurgiju, BeogradMayo Clinic and Foundation, Rochester, Minnesota, USAIn this study, the first complexes of Zn(II) with the N-benzyloxycar- bonyl-S-alaninato ligand (N-Boc-S-ala) were synthesized. The new complexes were characterized by elemental analysis, conductometric measurements, IR, 1H-NMR, 13C-NMR and 2D-NMR spectroscopy. On the basis of the experimental data, tetrahedral geometry of the Zn(II) complexes was proposed. A very good agreement between the NMR and DFT calculated data was obtained. Investigation of antimicrobial activity of the newly synthesized complexes was also performed. It was established that [Zn(N-Boc-S-ala)2] was selective and acts only on Candida albicans.http://www.doiserbia.nb.rs/img/doi/0352-5139/2008/0352-51390809815M.pdfantimicrobial activitydftn-benzyloxycarbonyl-s-alaninenmrzn(ii) complexes |
| spellingShingle | Mitić Dragana M. Miodragović Đenana U. Sladić Dušan M. Vitnik Željko J. Miodragović Zoran M. Anđelković Katarina K. Radulović Milanka Đ. Juranić Nenad O. Synthesis, NMR, DFT and antimicrobial studies of Zn(II) complexes with N-benzyloxycarbonyl-S-alanine Journal of the Serbian Chemical Society antimicrobial activity dft n-benzyloxycarbonyl-s-alanine nmr zn(ii) complexes |
| title | Synthesis, NMR, DFT and antimicrobial studies of Zn(II) complexes with N-benzyloxycarbonyl-S-alanine |
| title_full | Synthesis, NMR, DFT and antimicrobial studies of Zn(II) complexes with N-benzyloxycarbonyl-S-alanine |
| title_fullStr | Synthesis, NMR, DFT and antimicrobial studies of Zn(II) complexes with N-benzyloxycarbonyl-S-alanine |
| title_full_unstemmed | Synthesis, NMR, DFT and antimicrobial studies of Zn(II) complexes with N-benzyloxycarbonyl-S-alanine |
| title_short | Synthesis, NMR, DFT and antimicrobial studies of Zn(II) complexes with N-benzyloxycarbonyl-S-alanine |
| title_sort | synthesis nmr dft and antimicrobial studies of zn ii complexes with n benzyloxycarbonyl s alanine |
| topic | antimicrobial activity dft n-benzyloxycarbonyl-s-alanine nmr zn(ii) complexes |
| url | http://www.doiserbia.nb.rs/img/doi/0352-5139/2008/0352-51390809815M.pdf |
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