Slug and E-Cadherin: Stealth Accomplices?

Slug and E-Cadherin: Stealth Accomplices?

During physiological epithelial-mesenchymal transition (EMT), which is important for embryogenesis and wound healing, epithelial cells activate a program to remodel their structure and achieve a mesenchymal fate. In cancer cells, EMT confers increased invasiveness and tumor-initiating capacity, whic...

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Bibliographic Details
Main Authors: Esta Sterneck, Dipak K. Poria, Kuppusamy Balamurugan
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-07-01
Series:Frontiers in Molecular Biosciences
Subjects:
mammary gland
breast cancer
epithelial-mesenchymal transition (EMT)
E-cadherin (CDH1)
Slug (SNAI2)
basal
Online Access:https://www.frontiersin.org/article/10.3389/fmolb.2020.00138/full

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