Local cytokine status with laboratory animals in various periods after intraocular shape memory implant administration in experimental ophthalmology

Experimental estimation of pro- and anti-inflammatory cytokines balance in aqueous eye chamber liquid in case of intraocular implantation of drainage material made of nickelid titanium and intraocular application of a solid retention suture TH-10. Investigation of aqueous eye chamber liquid sampled...

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Main Authors: A. N. Steblyuk, N. V. Kolesnikova, V. E. Gunther
Format: Article
Language:Russian
Published: Ministry of Healthcare of the Russian Federation. “Kuban State Medical University” 2016-02-01
Series:Кубанский научный медицинский вестник
Subjects:
Online Access:https://ksma.elpub.ru/jour/article/view/469
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author A. N. Steblyuk
N. V. Kolesnikova
V. E. Gunther
author_facet A. N. Steblyuk
N. V. Kolesnikova
V. E. Gunther
author_sort A. N. Steblyuk
collection DOAJ
description Experimental estimation of pro- and anti-inflammatory cytokines balance in aqueous eye chamber liquid in case of intraocular implantation of drainage material made of nickelid titanium and intraocular application of a solid retention suture TH-10. Investigation of aqueous eye chamber liquid sampled on the 3rd, 7th and 30th days and in 3 months and in 1,5 year after intraocular implantation with nickelid titanium TH-10 used as a drainage and fixative device have been studied during experiment with 26 mature rabbits. The control group consisted of 6 intact rabbits as well as of 5 rabbits for whom perforating hypotensive surgical interference without drainage device implantation have been administered in various periods of monitoring. The opposite nature of cytokines balance changes and proportion of its pro- and anti-inflammatory element in the dynamics after intraocular implantation of a nickelid titanium and solid suture TH-10, which shows positive anti-inflammatory influence of materials made of nickelid titanium basis, that is manifested in significant reduction of anti-inflammatory component of cytokines balance and shows its maximum in the utmost tardy periods of monitoring, as well in clinically unresponsive postoperative course with animals of experimental group compared to the group of comparison.
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spelling doaj.art-46d9972221ea4c7bb25b1ce5facd6f122024-02-25T10:57:17ZrusMinistry of Healthcare of the Russian Federation. “Kuban State Medical University”Кубанский научный медицинский вестник1608-62282541-95442016-02-01113814210.25207/1608-6228-2016-1-138-142469Local cytokine status with laboratory animals in various periods after intraocular shape memory implant administration in experimental ophthalmologyA. N. Steblyuk0N. V. Kolesnikova1V. E. Gunther2Academician S. N. Fedorov Eye microsurgery complex, Krasnodar branchKuban state medical university of the Ministry of health of RussiaResearch Institute of shape memory material under Siberian physicotechnical Institute and Tomsk state universityExperimental estimation of pro- and anti-inflammatory cytokines balance in aqueous eye chamber liquid in case of intraocular implantation of drainage material made of nickelid titanium and intraocular application of a solid retention suture TH-10. Investigation of aqueous eye chamber liquid sampled on the 3rd, 7th and 30th days and in 3 months and in 1,5 year after intraocular implantation with nickelid titanium TH-10 used as a drainage and fixative device have been studied during experiment with 26 mature rabbits. The control group consisted of 6 intact rabbits as well as of 5 rabbits for whom perforating hypotensive surgical interference without drainage device implantation have been administered in various periods of monitoring. The opposite nature of cytokines balance changes and proportion of its pro- and anti-inflammatory element in the dynamics after intraocular implantation of a nickelid titanium and solid suture TH-10, which shows positive anti-inflammatory influence of materials made of nickelid titanium basis, that is manifested in significant reduction of anti-inflammatory component of cytokines balance and shows its maximum in the utmost tardy periods of monitoring, as well in clinically unresponsive postoperative course with animals of experimental group compared to the group of comparison.https://ksma.elpub.ru/jour/article/view/469цитокиныинтраокулярная имплантацияглаза животныхникелид титана»cytokinesintraocular implantationeyes of animalsnickelid titanium
spellingShingle A. N. Steblyuk
N. V. Kolesnikova
V. E. Gunther
Local cytokine status with laboratory animals in various periods after intraocular shape memory implant administration in experimental ophthalmology
Кубанский научный медицинский вестник
цитокины
интраокулярная имплантация
глаза животных
никелид титана»
cytokines
intraocular implantation
eyes of animals
nickelid titanium
title Local cytokine status with laboratory animals in various periods after intraocular shape memory implant administration in experimental ophthalmology
title_full Local cytokine status with laboratory animals in various periods after intraocular shape memory implant administration in experimental ophthalmology
title_fullStr Local cytokine status with laboratory animals in various periods after intraocular shape memory implant administration in experimental ophthalmology
title_full_unstemmed Local cytokine status with laboratory animals in various periods after intraocular shape memory implant administration in experimental ophthalmology
title_short Local cytokine status with laboratory animals in various periods after intraocular shape memory implant administration in experimental ophthalmology
title_sort local cytokine status with laboratory animals in various periods after intraocular shape memory implant administration in experimental ophthalmology
topic цитокины
интраокулярная имплантация
глаза животных
никелид титана»
cytokines
intraocular implantation
eyes of animals
nickelid titanium
url https://ksma.elpub.ru/jour/article/view/469
work_keys_str_mv AT ansteblyuk localcytokinestatuswithlaboratoryanimalsinvariousperiodsafterintraocularshapememoryimplantadministrationinexperimentalophthalmology
AT nvkolesnikova localcytokinestatuswithlaboratoryanimalsinvariousperiodsafterintraocularshapememoryimplantadministrationinexperimentalophthalmology
AT vegunther localcytokinestatuswithlaboratoryanimalsinvariousperiodsafterintraocularshapememoryimplantadministrationinexperimentalophthalmology