Comparative evaluations of the Monte Carlo-based light propagation simulation packages for optical imaging

Monte Carlo simulation of light propagation in turbid medium has been studied for years. A number of software packages have been developed to handle with such issue. However, it is hard to compare these simulation packages, especially for tissues with complex heterogeneous structures. Here, we first...

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Main Authors: Lin Wang, Shenghan Ren, Xueli Chen
Format: Article
Language:English
Published: World Scientific Publishing 2018-01-01
Series:Journal of Innovative Optical Health Sciences
Subjects:
Online Access:http://www.worldscientific.com/doi/pdf/10.1142/S1793545817500171
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author Lin Wang
Shenghan Ren
Xueli Chen
author_facet Lin Wang
Shenghan Ren
Xueli Chen
author_sort Lin Wang
collection DOAJ
description Monte Carlo simulation of light propagation in turbid medium has been studied for years. A number of software packages have been developed to handle with such issue. However, it is hard to compare these simulation packages, especially for tissues with complex heterogeneous structures. Here, we first designed a group of mesh datasets generated by Iso2Mesh software, and used them to cross-validate the accuracy and to evaluate the performance of four Monte Carlo-based simulation packages, including Monte Carlo model of steady-state light transport in multi-layered tissues (MCML), tetrahedron-based inhomogeneous Monte Carlo optical simulator (TIMOS), Molecular Optical Simulation Environment (MOSE), and Mesh-based Monte Carlo (MMC). The performance of each package was evaluated based on the designed mesh datasets. The merits and demerits of each package were also discussed. Comparative results showed that the TIMOS package provided the best performance, which proved to be a reliable, efficient, and stable MC simulation package for users.
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spelling doaj.art-46db778d686e460588c1859ae9233efc2022-12-22T02:59:20ZengWorld Scientific PublishingJournal of Innovative Optical Health Sciences1793-54581793-72052018-01-011111750017-11750017-1010.1142/S179354581750017110.1142/S1793545817500171Comparative evaluations of the Monte Carlo-based light propagation simulation packages for optical imagingLin Wang0Shenghan Ren1Xueli Chen2School of Information Sciences and Technology, Northwest University, Xi’an Shaanxi 710127, P. R. ChinaEngineering Research Center of Molecular and Neuro Imaging of Ministry of Education, School of Life Science and Technology, Xidian University, Xi’an Shaanxi 710126, P. R. ChinaEngineering Research Center of Molecular and Neuro Imaging of Ministry of Education, School of Life Science and Technology, Xidian University, Xi’an Shaanxi 710126, P. R. ChinaMonte Carlo simulation of light propagation in turbid medium has been studied for years. A number of software packages have been developed to handle with such issue. However, it is hard to compare these simulation packages, especially for tissues with complex heterogeneous structures. Here, we first designed a group of mesh datasets generated by Iso2Mesh software, and used them to cross-validate the accuracy and to evaluate the performance of four Monte Carlo-based simulation packages, including Monte Carlo model of steady-state light transport in multi-layered tissues (MCML), tetrahedron-based inhomogeneous Monte Carlo optical simulator (TIMOS), Molecular Optical Simulation Environment (MOSE), and Mesh-based Monte Carlo (MMC). The performance of each package was evaluated based on the designed mesh datasets. The merits and demerits of each package were also discussed. Comparative results showed that the TIMOS package provided the best performance, which proved to be a reliable, efficient, and stable MC simulation package for users.http://www.worldscientific.com/doi/pdf/10.1142/S1793545817500171Light transportMonte Carlocomparative evaluationmesh datasets
spellingShingle Lin Wang
Shenghan Ren
Xueli Chen
Comparative evaluations of the Monte Carlo-based light propagation simulation packages for optical imaging
Journal of Innovative Optical Health Sciences
Light transport
Monte Carlo
comparative evaluation
mesh datasets
title Comparative evaluations of the Monte Carlo-based light propagation simulation packages for optical imaging
title_full Comparative evaluations of the Monte Carlo-based light propagation simulation packages for optical imaging
title_fullStr Comparative evaluations of the Monte Carlo-based light propagation simulation packages for optical imaging
title_full_unstemmed Comparative evaluations of the Monte Carlo-based light propagation simulation packages for optical imaging
title_short Comparative evaluations of the Monte Carlo-based light propagation simulation packages for optical imaging
title_sort comparative evaluations of the monte carlo based light propagation simulation packages for optical imaging
topic Light transport
Monte Carlo
comparative evaluation
mesh datasets
url http://www.worldscientific.com/doi/pdf/10.1142/S1793545817500171
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AT shenghanren comparativeevaluationsofthemontecarlobasedlightpropagationsimulationpackagesforopticalimaging
AT xuelichen comparativeevaluationsofthemontecarlobasedlightpropagationsimulationpackagesforopticalimaging