Inhibition of corticosterone synthesis impairs cued water maze consolidation, but it does not affect the expression of BDNF, CK2 and SGK1 genes in dorsal striatum

Inhibition of corticosterone synthesis impairs cued water maze consolidation, but it does not affect the expression of BDNF, CK2 and SGK1 genes in dorsal striatum

Corticosterone (CORT) release during learning experiences is associated with strong memories and activity of the glucocorticoid receptor. It has been shown that lesions of the dorsal striatum (DS) of rats trained in the cued version of the Morris water maze impair memory, and that local injection of...

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Bibliographic Details
Main Authors: Rogelio Pegueros-Maldonado, Santiago M. Pech-Pool, Jaisson J. Blancas, Roberto A. Prado-Alcalá, Carlos Arámburo, Maricela Luna, Gina L. Quirarte
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-02-01
Series:Frontiers in Behavioral Neuroscience
Subjects:
cued Morris water maze
corticosterone
glucocorticoid receptor
dorsal striatum
memory consolidation
Online Access:https://www.frontiersin.org/articles/10.3389/fnbeh.2024.1341883/full

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