Hydrogel Based on Crosslinked Methylcellulose Prepared by Electron Beam Irradiation for Wound Dressing Application
The aim of this research is to explore the possibility of methylcellulose polymer to be used as wound dressing material prepared using electron beam technique. The methylcellulose paste solution with various of molecular weight (SM-4, SM-100, SM-400, SM-4000 and SM-8000) at different concentration (...
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| Format: | Article |
| Language: | English |
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Department of Chemistry, Universitas Gadjah Mada
2014-10-01
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| Series: | Indonesian Journal of Chemistry |
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| Online Access: | https://jurnal.ugm.ac.id/ijc/article/view/21237 |
| _version_ | 1818738048157876224 |
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| author | Ambyah Suliwarno |
| author_facet | Ambyah Suliwarno |
| author_sort | Ambyah Suliwarno |
| collection | DOAJ |
| description | The aim of this research is to explore the possibility of methylcellulose polymer to be used as wound dressing material prepared using electron beam technique. The methylcellulose paste solution with various of molecular weight (SM-4, SM-100, SM-400, SM-4000 and SM-8000) at different concentration (15-30% w/v) were irradiated by using electron beam on the dose range of 10 kGy up to 40 kGy. Gel fraction and swelling ratio of hydrogels were determined gravimetrically. Tensile strength and elasticity of hydrogels were measured using a universal testing machine. It was found that with the increasing of irradiation dose from 10 up to 40 kGy, gel fraction and tensile strength were increased for all of hydrogels with various of molecular weight. On contrary, the swelling ratio of hydrogels decreased with increasing of irradiation dose. The optimum hydrogels elasticity were obtained from methylcellulose solution with the concentration range of 15-20% with irradiation dose of 20 kGy and showed excellent performance. The hydrogels based on methylcellulose prepared by electron beam irradiation can be considered for wound dressing material. |
| first_indexed | 2024-12-18T01:02:44Z |
| format | Article |
| id | doaj.art-46dd89a948e94bc7b83619b952852992 |
| institution | Directory Open Access Journal |
| issn | 1411-9420 2460-1578 |
| language | English |
| last_indexed | 2024-12-18T01:02:44Z |
| publishDate | 2014-10-01 |
| publisher | Department of Chemistry, Universitas Gadjah Mada |
| record_format | Article |
| series | Indonesian Journal of Chemistry |
| spelling | doaj.art-46dd89a948e94bc7b83619b9528529922022-12-21T21:26:19ZengDepartment of Chemistry, Universitas Gadjah MadaIndonesian Journal of Chemistry1411-94202460-15782014-10-0114326226810.22146/ijc.2123714335Hydrogel Based on Crosslinked Methylcellulose Prepared by Electron Beam Irradiation for Wound Dressing ApplicationAmbyah Suliwarno0Center of Isotopes and Radiation Application–National Nuclear Energy Agency (BATAN), Jl. Lebak Bulus Raya No 49 Jakarta 12440The aim of this research is to explore the possibility of methylcellulose polymer to be used as wound dressing material prepared using electron beam technique. The methylcellulose paste solution with various of molecular weight (SM-4, SM-100, SM-400, SM-4000 and SM-8000) at different concentration (15-30% w/v) were irradiated by using electron beam on the dose range of 10 kGy up to 40 kGy. Gel fraction and swelling ratio of hydrogels were determined gravimetrically. Tensile strength and elasticity of hydrogels were measured using a universal testing machine. It was found that with the increasing of irradiation dose from 10 up to 40 kGy, gel fraction and tensile strength were increased for all of hydrogels with various of molecular weight. On contrary, the swelling ratio of hydrogels decreased with increasing of irradiation dose. The optimum hydrogels elasticity were obtained from methylcellulose solution with the concentration range of 15-20% with irradiation dose of 20 kGy and showed excellent performance. The hydrogels based on methylcellulose prepared by electron beam irradiation can be considered for wound dressing material.https://jurnal.ugm.ac.id/ijc/article/view/21237methylcellulosemolecular weightelectron beam irradiationwound dressing |
| spellingShingle | Ambyah Suliwarno Hydrogel Based on Crosslinked Methylcellulose Prepared by Electron Beam Irradiation for Wound Dressing Application Indonesian Journal of Chemistry methylcellulose molecular weight electron beam irradiation wound dressing |
| title | Hydrogel Based on Crosslinked Methylcellulose Prepared by Electron Beam Irradiation for Wound Dressing Application |
| title_full | Hydrogel Based on Crosslinked Methylcellulose Prepared by Electron Beam Irradiation for Wound Dressing Application |
| title_fullStr | Hydrogel Based on Crosslinked Methylcellulose Prepared by Electron Beam Irradiation for Wound Dressing Application |
| title_full_unstemmed | Hydrogel Based on Crosslinked Methylcellulose Prepared by Electron Beam Irradiation for Wound Dressing Application |
| title_short | Hydrogel Based on Crosslinked Methylcellulose Prepared by Electron Beam Irradiation for Wound Dressing Application |
| title_sort | hydrogel based on crosslinked methylcellulose prepared by electron beam irradiation for wound dressing application |
| topic | methylcellulose molecular weight electron beam irradiation wound dressing |
| url | https://jurnal.ugm.ac.id/ijc/article/view/21237 |
| work_keys_str_mv | AT ambyahsuliwarno hydrogelbasedoncrosslinkedmethylcellulosepreparedbyelectronbeamirradiationforwounddressingapplication |