Immune protection against Trypanosoma cruzi induced by TcVac4 in a canine model.
Chagas disease, caused by Trypanosoma cruzi, is endemic in southern parts of the American continent. Herein, we have tested the protective efficacy of a DNA-prime/T. rangeli-boost (TcVac4) vaccine in a dog (Canis familiaris) model. Dogs were immunized with two-doses of DNA vaccine (pcDNA3.1 encoding...
| Main Authors: | , , , , , , , , , , , , , |
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| 格式: | 文件 |
| 语言: | English |
| 出版: |
Public Library of Science (PLoS)
2015-04-01
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| 丛编: | PLoS Neglected Tropical Diseases |
| 在线阅读: | http://europepmc.org/articles/PMC4390229?pdf=render |