Advances in Laboratory Diagnosis of Bacterial Vaginosis

Bacterial vaginosis (BV), an imbalance of normal vaginal microecology, is manifested as a mixed infection. It is characterized by a decrease of normal hydrogen peroxide-producing lactobacillus and an overgrowth of anaerobic bacteria (mobiluncus, prevotella) and facultative bacteria (gardnerella vagi...

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Main Authors: WANG Zhe, ZHAO Ying, XU Yingchun
Format: Article
Language:zho
Published: Editorial Office of Medical Journal of Peking Union Medical College Hospital 2023-09-01
Series:Xiehe Yixue Zazhi
Subjects:
Online Access:https://xhyxzz.pumch.cn/en/article/doi/10.12290/xhyxzz.2022-0677
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author WANG Zhe
ZHAO Ying
XU Yingchun
author_facet WANG Zhe
ZHAO Ying
XU Yingchun
author_sort WANG Zhe
collection DOAJ
description Bacterial vaginosis (BV), an imbalance of normal vaginal microecology, is manifested as a mixed infection. It is characterized by a decrease of normal hydrogen peroxide-producing lactobacillus and an overgrowth of anaerobic bacteria (mobiluncus, prevotella) and facultative bacteria (gardnerella vaginalis, atopo vaginalis). BV is a risk factor for pelvic inflammatory disease, infertility, sexually transmitted pathogens (human papillomavirus, human immunodeficiency virus, neisseria gonorrhoeae, chlamydia trachomatis, etc.) infection. In addition, BV during pregnancy can lead to adverse obstetrical outcomes, including early miscarriage, premature delivery, postpartum endometritis, and low birth weight. The pathogens causing BV are diverse and have a high recurrence rate after treatment. About 10% to 50% of BV patients have no clinical symptoms and are easy to miss diagnosis. Rapid and accurate laboratory detection can provide timely diagnosis and treatment for BV patients and avoid adverse outcomes. Therefore, this paper reviews the research progress of diagnostic criteria, vaginal microecological evaluation and novel detection methods for BV, in order to provide reference for clinical diagnosis and treatment of BV.
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spelling doaj.art-46e09ec41a4f4a79ace097131b9304c02023-10-09T09:02:06ZzhoEditorial Office of Medical Journal of Peking Union Medical College HospitalXiehe Yixue Zazhi1674-90812023-09-011451053105910.12290/xhyxzz.2022-0677Advances in Laboratory Diagnosis of Bacterial VaginosisWANG ZheZHAO YingXU YingchunBacterial vaginosis (BV), an imbalance of normal vaginal microecology, is manifested as a mixed infection. It is characterized by a decrease of normal hydrogen peroxide-producing lactobacillus and an overgrowth of anaerobic bacteria (mobiluncus, prevotella) and facultative bacteria (gardnerella vaginalis, atopo vaginalis). BV is a risk factor for pelvic inflammatory disease, infertility, sexually transmitted pathogens (human papillomavirus, human immunodeficiency virus, neisseria gonorrhoeae, chlamydia trachomatis, etc.) infection. In addition, BV during pregnancy can lead to adverse obstetrical outcomes, including early miscarriage, premature delivery, postpartum endometritis, and low birth weight. The pathogens causing BV are diverse and have a high recurrence rate after treatment. About 10% to 50% of BV patients have no clinical symptoms and are easy to miss diagnosis. Rapid and accurate laboratory detection can provide timely diagnosis and treatment for BV patients and avoid adverse outcomes. Therefore, this paper reviews the research progress of diagnostic criteria, vaginal microecological evaluation and novel detection methods for BV, in order to provide reference for clinical diagnosis and treatment of BV.https://xhyxzz.pumch.cn/en/article/doi/10.12290/xhyxzz.2022-0677bacterial vaginosislaboratory diagnosisvaginal microbiome
spellingShingle WANG Zhe
ZHAO Ying
XU Yingchun
Advances in Laboratory Diagnosis of Bacterial Vaginosis
Xiehe Yixue Zazhi
bacterial vaginosis
laboratory diagnosis
vaginal microbiome
title Advances in Laboratory Diagnosis of Bacterial Vaginosis
title_full Advances in Laboratory Diagnosis of Bacterial Vaginosis
title_fullStr Advances in Laboratory Diagnosis of Bacterial Vaginosis
title_full_unstemmed Advances in Laboratory Diagnosis of Bacterial Vaginosis
title_short Advances in Laboratory Diagnosis of Bacterial Vaginosis
title_sort advances in laboratory diagnosis of bacterial vaginosis
topic bacterial vaginosis
laboratory diagnosis
vaginal microbiome
url https://xhyxzz.pumch.cn/en/article/doi/10.12290/xhyxzz.2022-0677
work_keys_str_mv AT wangzhe advancesinlaboratorydiagnosisofbacterialvaginosis
AT zhaoying advancesinlaboratorydiagnosisofbacterialvaginosis
AT xuyingchun advancesinlaboratorydiagnosisofbacterialvaginosis