Advances in Laboratory Diagnosis of Bacterial Vaginosis
Bacterial vaginosis (BV), an imbalance of normal vaginal microecology, is manifested as a mixed infection. It is characterized by a decrease of normal hydrogen peroxide-producing lactobacillus and an overgrowth of anaerobic bacteria (mobiluncus, prevotella) and facultative bacteria (gardnerella vagi...
Main Authors: | , , |
---|---|
Format: | Article |
Language: | zho |
Published: |
Editorial Office of Medical Journal of Peking Union Medical College Hospital
2023-09-01
|
Series: | Xiehe Yixue Zazhi |
Subjects: | |
Online Access: | https://xhyxzz.pumch.cn/en/article/doi/10.12290/xhyxzz.2022-0677 |
_version_ | 1797663465358229504 |
---|---|
author | WANG Zhe ZHAO Ying XU Yingchun |
author_facet | WANG Zhe ZHAO Ying XU Yingchun |
author_sort | WANG Zhe |
collection | DOAJ |
description | Bacterial vaginosis (BV), an imbalance of normal vaginal microecology, is manifested as a mixed infection. It is characterized by a decrease of normal hydrogen peroxide-producing lactobacillus and an overgrowth of anaerobic bacteria (mobiluncus, prevotella) and facultative bacteria (gardnerella vaginalis, atopo vaginalis). BV is a risk factor for pelvic inflammatory disease, infertility, sexually transmitted pathogens (human papillomavirus, human immunodeficiency virus, neisseria gonorrhoeae, chlamydia trachomatis, etc.) infection. In addition, BV during pregnancy can lead to adverse obstetrical outcomes, including early miscarriage, premature delivery, postpartum endometritis, and low birth weight. The pathogens causing BV are diverse and have a high recurrence rate after treatment. About 10% to 50% of BV patients have no clinical symptoms and are easy to miss diagnosis. Rapid and accurate laboratory detection can provide timely diagnosis and treatment for BV patients and avoid adverse outcomes. Therefore, this paper reviews the research progress of diagnostic criteria, vaginal microecological evaluation and novel detection methods for BV, in order to provide reference for clinical diagnosis and treatment of BV. |
first_indexed | 2024-03-11T19:15:02Z |
format | Article |
id | doaj.art-46e09ec41a4f4a79ace097131b9304c0 |
institution | Directory Open Access Journal |
issn | 1674-9081 |
language | zho |
last_indexed | 2024-03-11T19:15:02Z |
publishDate | 2023-09-01 |
publisher | Editorial Office of Medical Journal of Peking Union Medical College Hospital |
record_format | Article |
series | Xiehe Yixue Zazhi |
spelling | doaj.art-46e09ec41a4f4a79ace097131b9304c02023-10-09T09:02:06ZzhoEditorial Office of Medical Journal of Peking Union Medical College HospitalXiehe Yixue Zazhi1674-90812023-09-011451053105910.12290/xhyxzz.2022-0677Advances in Laboratory Diagnosis of Bacterial VaginosisWANG ZheZHAO YingXU YingchunBacterial vaginosis (BV), an imbalance of normal vaginal microecology, is manifested as a mixed infection. It is characterized by a decrease of normal hydrogen peroxide-producing lactobacillus and an overgrowth of anaerobic bacteria (mobiluncus, prevotella) and facultative bacteria (gardnerella vaginalis, atopo vaginalis). BV is a risk factor for pelvic inflammatory disease, infertility, sexually transmitted pathogens (human papillomavirus, human immunodeficiency virus, neisseria gonorrhoeae, chlamydia trachomatis, etc.) infection. In addition, BV during pregnancy can lead to adverse obstetrical outcomes, including early miscarriage, premature delivery, postpartum endometritis, and low birth weight. The pathogens causing BV are diverse and have a high recurrence rate after treatment. About 10% to 50% of BV patients have no clinical symptoms and are easy to miss diagnosis. Rapid and accurate laboratory detection can provide timely diagnosis and treatment for BV patients and avoid adverse outcomes. Therefore, this paper reviews the research progress of diagnostic criteria, vaginal microecological evaluation and novel detection methods for BV, in order to provide reference for clinical diagnosis and treatment of BV.https://xhyxzz.pumch.cn/en/article/doi/10.12290/xhyxzz.2022-0677bacterial vaginosislaboratory diagnosisvaginal microbiome |
spellingShingle | WANG Zhe ZHAO Ying XU Yingchun Advances in Laboratory Diagnosis of Bacterial Vaginosis Xiehe Yixue Zazhi bacterial vaginosis laboratory diagnosis vaginal microbiome |
title | Advances in Laboratory Diagnosis of Bacterial Vaginosis |
title_full | Advances in Laboratory Diagnosis of Bacterial Vaginosis |
title_fullStr | Advances in Laboratory Diagnosis of Bacterial Vaginosis |
title_full_unstemmed | Advances in Laboratory Diagnosis of Bacterial Vaginosis |
title_short | Advances in Laboratory Diagnosis of Bacterial Vaginosis |
title_sort | advances in laboratory diagnosis of bacterial vaginosis |
topic | bacterial vaginosis laboratory diagnosis vaginal microbiome |
url | https://xhyxzz.pumch.cn/en/article/doi/10.12290/xhyxzz.2022-0677 |
work_keys_str_mv | AT wangzhe advancesinlaboratorydiagnosisofbacterialvaginosis AT zhaoying advancesinlaboratorydiagnosisofbacterialvaginosis AT xuyingchun advancesinlaboratorydiagnosisofbacterialvaginosis |