Molecular Subtypes of High-Grade Neuroendocrine Carcinoma (HGNEC): What is YAP1-Positive HGNEC?

Molecular Subtypes of High-Grade Neuroendocrine Carcinoma (HGNEC): What is YAP1-Positive HGNEC?

Small cell lung cancer (SCLC) subtype classification, based on high-level expression of key transcriptional regulators; ASCL1 (SCLC-A), NEUROD1 (SCLC-N), POU2F3 (SCLC-P), and YAP1 (SCLC-Y), has recently been proposed. YAP1 (and POU2F3) has attracted attention as an important factor for non-neuroendo...

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Bibliographic Details
Main Authors: Hitomi Kawai, Ryouta Matsuoka, Takeshi Ito, Daisuke Matsubara
Format: Article
Language:English
Published: IMR Press 2022-03-01
Series:Frontiers in Bioscience-Landmark
Subjects:
review
yap1
sclc
lcnec
hgnec
sclc-y
sclc-i
chemo-sensitivity
Online Access:https://www.imrpress.com/journal/FBL/27/3/10.31083/j.fbl2703108

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