Long-Circulating Hyaluronan-Based Nanohydrogels as Carriers of Hydrophobic Drugs

Long-Circulating Hyaluronan-Based Nanohydrogels as Carriers of Hydrophobic Drugs

Nanohydrogels based on natural polymers, such as polysaccharides, are gaining interest as vehicles for therapeutic agents, as they can modify the pharmacokinetics and pharmacodynamics of the carried drugs. In this work, hyaluronan-riboflavin nanohydrogels were tested in vivo in healthy rats highligh...

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Bibliographic Details
Main Authors: Chiara Di Meo, Mayte Martínez-Martínez, Tommasina Coviello, Marival Bermejo, Virginia Merino, Isabel Gonzalez-Alvarez, Marta Gonzalez-Alvarez, Pietro Matricardi
Format: Article
Language:English
Published: MDPI AG 2018-11-01
Series:Pharmaceutics
Subjects:
nanohydrogels
hyaluronan
riboflavin
hydrophobic drugs
piroxicam
biodistribution
pharmacokinetic
Online Access:https://www.mdpi.com/1999-4923/10/4/213

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