Advances and Challenges in Diagnostics of Toxoplasmosis in HIV-Infected Patients

<i>Toxoplasma gondii</i> is a worldwide distributed protozoan parasite. This apicomplexan parasite infects one-third of the population worldwide, causing toxoplasmosis, considered one of the neglected parasitic infections. In healthy humans, most infections are asymptomatic. However, in...

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Main Authors: Roland Wesołowski, Marta Pawłowska, Małgorzata Smoguła, Karolina Szewczyk-Golec
Format: Article
Language:English
Published: MDPI AG 2023-01-01
Series:Pathogens
Subjects:
Online Access:https://www.mdpi.com/2076-0817/12/1/110
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author Roland Wesołowski
Marta Pawłowska
Małgorzata Smoguła
Karolina Szewczyk-Golec
author_facet Roland Wesołowski
Marta Pawłowska
Małgorzata Smoguła
Karolina Szewczyk-Golec
author_sort Roland Wesołowski
collection DOAJ
description <i>Toxoplasma gondii</i> is a worldwide distributed protozoan parasite. This apicomplexan parasite infects one-third of the population worldwide, causing toxoplasmosis, considered one of the neglected parasitic infections. In healthy humans, most infections are asymptomatic. However, in immunocompromised patients, the course of the disease can be life-threatening. Human immunodeficiency virus (HIV)-infected patients have a very high burden of <i>Toxoplasma gondii</i> co-infection. Thus, it is essential to use modern, sensitive, and specific methods to properly monitor the course of toxoplasmosis in immunodeficient patients.
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spelling doaj.art-46e6bc18f946492fb52fc2ecc17cd8732023-11-30T23:53:51ZengMDPI AGPathogens2076-08172023-01-0112111010.3390/pathogens12010110Advances and Challenges in Diagnostics of Toxoplasmosis in HIV-Infected PatientsRoland Wesołowski0Marta Pawłowska1Małgorzata Smoguła2Karolina Szewczyk-Golec3Department of Medical Biology and Biochemistry, Ludwik Rydygier Collegium Medicum in Bydgoszcz, Nicolaus Copernicus University in Toruń, 87-100 Toruń, PolandDepartment of Medical Biology and Biochemistry, Ludwik Rydygier Collegium Medicum in Bydgoszcz, Nicolaus Copernicus University in Toruń, 87-100 Toruń, PolandDepartment of Medical Biology and Biochemistry, Ludwik Rydygier Collegium Medicum in Bydgoszcz, Nicolaus Copernicus University in Toruń, 87-100 Toruń, PolandDepartment of Medical Biology and Biochemistry, Ludwik Rydygier Collegium Medicum in Bydgoszcz, Nicolaus Copernicus University in Toruń, 87-100 Toruń, Poland<i>Toxoplasma gondii</i> is a worldwide distributed protozoan parasite. This apicomplexan parasite infects one-third of the population worldwide, causing toxoplasmosis, considered one of the neglected parasitic infections. In healthy humans, most infections are asymptomatic. However, in immunocompromised patients, the course of the disease can be life-threatening. Human immunodeficiency virus (HIV)-infected patients have a very high burden of <i>Toxoplasma gondii</i> co-infection. Thus, it is essential to use modern, sensitive, and specific methods to properly monitor the course of toxoplasmosis in immunodeficient patients.https://www.mdpi.com/2076-0817/12/1/110toxoplasmosisHIVdiagnostics<i>Toxoplasma gondii</i>
spellingShingle Roland Wesołowski
Marta Pawłowska
Małgorzata Smoguła
Karolina Szewczyk-Golec
Advances and Challenges in Diagnostics of Toxoplasmosis in HIV-Infected Patients
Pathogens
toxoplasmosis
HIV
diagnostics
<i>Toxoplasma gondii</i>
title Advances and Challenges in Diagnostics of Toxoplasmosis in HIV-Infected Patients
title_full Advances and Challenges in Diagnostics of Toxoplasmosis in HIV-Infected Patients
title_fullStr Advances and Challenges in Diagnostics of Toxoplasmosis in HIV-Infected Patients
title_full_unstemmed Advances and Challenges in Diagnostics of Toxoplasmosis in HIV-Infected Patients
title_short Advances and Challenges in Diagnostics of Toxoplasmosis in HIV-Infected Patients
title_sort advances and challenges in diagnostics of toxoplasmosis in hiv infected patients
topic toxoplasmosis
HIV
diagnostics
<i>Toxoplasma gondii</i>
url https://www.mdpi.com/2076-0817/12/1/110
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AT martapawłowska advancesandchallengesindiagnosticsoftoxoplasmosisinhivinfectedpatients
AT małgorzatasmoguła advancesandchallengesindiagnosticsoftoxoplasmosisinhivinfectedpatients
AT karolinaszewczykgolec advancesandchallengesindiagnosticsoftoxoplasmosisinhivinfectedpatients