Simultaneous determination of pethidine pharmacokinetics in rats: The impact of tramadol coadministration

Simultaneous determination of pethidine pharmacokinetics in rats: The impact of tramadol coadministration

The rats model has never thoroughly investigated the influence of tramadol on plasma pethidine concentration besides pethidine pharmacokinetics. Individually, analgesic ED<sub>50</sub>s for pethidine and tramadol are estimated as 3.55 and 24.21 mg/kg, i.p. Subsequently, their measures de...

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Bibliographic Details
Main Authors:	Yaareb J. Mousa, Mahmood B. Mahmood, Zainab T. Mohammed
Format:	Article
Language:	Arabic
Published:	University of Mosul, College of Veterinary Medicine 2023-01-01
Series:	Iraqi Journal of Veterinary Sciences
Subjects:	pethidine pharmacokinetics plasma rats tramadol
Online Access:	https://www.vetmedmosul.com/article_176550_e468ffcf6d1cd62e5c0c7fdf841e0d3b.pdf

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