Fulminant Type 1 Diabetes in an 81-Year-Old Male with Rhabdomyolysis-Induced Acute Kidney Injury Successfully Withdrawn from Hemodialysis: A Case Report
ABSTRACT: Objective: Fulminant type 1 diabetes mellitus (FT1DM), a distinct subtype of type 1 diabetes, is characterized by a rapid onset of severe hyperglycemia and diabetic ketoacidosis (DKA). DKA sometimes induces severe rhabdomyolysis, which causes renal failure, and it requires permanent hemodi...
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| Format: | Article |
| Language: | English |
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Elsevier
2015-01-01
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| Series: | AACE Clinical Case Reports |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2376060520302510 |
| _version_ | 1818596536689360896 |
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| author | Satoshi Yamagata, MD, PhD Kazunori Kageyama, MD, PhD Jun Matsui, MD, PhD Hiroshi Murakami, MD, PhD Maki Yamashita, MD, PhD Shingo Murasawa, MD Miyuki Yanagimachi, MD, PhD Makoto Daimon, MD, PhD |
| author_facet | Satoshi Yamagata, MD, PhD Kazunori Kageyama, MD, PhD Jun Matsui, MD, PhD Hiroshi Murakami, MD, PhD Maki Yamashita, MD, PhD Shingo Murasawa, MD Miyuki Yanagimachi, MD, PhD Makoto Daimon, MD, PhD |
| author_sort | Satoshi Yamagata, MD, PhD |
| collection | DOAJ |
| description | ABSTRACT: Objective: Fulminant type 1 diabetes mellitus (FT1DM), a distinct subtype of type 1 diabetes, is characterized by a rapid onset of severe hyperglycemia and diabetic ketoacidosis (DKA). DKA sometimes induces severe rhabdomyolysis, which causes renal failure, and it requires permanent hemodialysis (HD), especially in elderly patients. Some cases of FT1DM progress to rhabdomyolysis-induced acute kidney injury (AKI).Methods: We report the case of an 81-year-old male with rhabdomyolysis-induced AKI, the oldest patient reported to date, associated with acute FT1DM onset.Results: Although the patient required HD, he was successfully withdrawn from HD within 2 months.Conclusion: Even in such advanced age patients, prompt renal replacement therapy gives the prospect for recovering kidney function and circumvents the need for permanent renal replacement therapy.Abbreviations: AKI acute kidney injury CHDF continuous hemodiafiltration CK creatinine kinase DKA diabetic ketoacidosis FT1DM fulminant type 1 diabetes mellitus HD hemodialysis HLA human leukocyte antigen RRT renal replacement therapy |
| first_indexed | 2024-12-16T11:33:28Z |
| format | Article |
| id | doaj.art-46e84c5b49be4eaf9d1873bf805bef85 |
| institution | Directory Open Access Journal |
| issn | 2376-0605 |
| language | English |
| last_indexed | 2024-12-16T11:33:28Z |
| publishDate | 2015-01-01 |
| publisher | Elsevier |
| record_format | Article |
| series | AACE Clinical Case Reports |
| spelling | doaj.art-46e84c5b49be4eaf9d1873bf805bef852022-12-21T22:33:10ZengElsevierAACE Clinical Case Reports2376-06052015-01-0113e208e211Fulminant Type 1 Diabetes in an 81-Year-Old Male with Rhabdomyolysis-Induced Acute Kidney Injury Successfully Withdrawn from Hemodialysis: A Case ReportSatoshi Yamagata, MD, PhD0Kazunori Kageyama, MD, PhD1Jun Matsui, MD, PhD2Hiroshi Murakami, MD, PhD3Maki Yamashita, MD, PhD4Shingo Murasawa, MD5Miyuki Yanagimachi, MD, PhD6Makoto Daimon, MD, PhD7From the Department of Endocrinology and Metabolism, Hirosaki University Graduate School of Medicine, 5 Zaifu-cho, Hirosaki, Aomori 036-8562, Japan.; Address correspondence to Dr. Satoshi Yamagata; Department of Endocrinology and Metabolism, Hirosaki University Graduate School of Medicine, 5 Zaifu-cho, Hirosaki, Aomori 036-8562, Japan.From the Department of Endocrinology and Metabolism, Hirosaki University Graduate School of Medicine, 5 Zaifu-cho, Hirosaki, Aomori 036-8562, Japan.From the Department of Endocrinology and Metabolism, Hirosaki University Graduate School of Medicine, 5 Zaifu-cho, Hirosaki, Aomori 036-8562, Japan.From the Department of Endocrinology and Metabolism, Hirosaki University Graduate School of Medicine, 5 Zaifu-cho, Hirosaki, Aomori 036-8562, Japan.From the Department of Endocrinology and Metabolism, Hirosaki University Graduate School of Medicine, 5 Zaifu-cho, Hirosaki, Aomori 036-8562, Japan.From the Department of Endocrinology and Metabolism, Hirosaki University Graduate School of Medicine, 5 Zaifu-cho, Hirosaki, Aomori 036-8562, Japan.From the Department of Endocrinology and Metabolism, Hirosaki University Graduate School of Medicine, 5 Zaifu-cho, Hirosaki, Aomori 036-8562, Japan.From the Department of Endocrinology and Metabolism, Hirosaki University Graduate School of Medicine, 5 Zaifu-cho, Hirosaki, Aomori 036-8562, Japan.ABSTRACT: Objective: Fulminant type 1 diabetes mellitus (FT1DM), a distinct subtype of type 1 diabetes, is characterized by a rapid onset of severe hyperglycemia and diabetic ketoacidosis (DKA). DKA sometimes induces severe rhabdomyolysis, which causes renal failure, and it requires permanent hemodialysis (HD), especially in elderly patients. Some cases of FT1DM progress to rhabdomyolysis-induced acute kidney injury (AKI).Methods: We report the case of an 81-year-old male with rhabdomyolysis-induced AKI, the oldest patient reported to date, associated with acute FT1DM onset.Results: Although the patient required HD, he was successfully withdrawn from HD within 2 months.Conclusion: Even in such advanced age patients, prompt renal replacement therapy gives the prospect for recovering kidney function and circumvents the need for permanent renal replacement therapy.Abbreviations: AKI acute kidney injury CHDF continuous hemodiafiltration CK creatinine kinase DKA diabetic ketoacidosis FT1DM fulminant type 1 diabetes mellitus HD hemodialysis HLA human leukocyte antigen RRT renal replacement therapyhttp://www.sciencedirect.com/science/article/pii/S2376060520302510 |
| spellingShingle | Satoshi Yamagata, MD, PhD Kazunori Kageyama, MD, PhD Jun Matsui, MD, PhD Hiroshi Murakami, MD, PhD Maki Yamashita, MD, PhD Shingo Murasawa, MD Miyuki Yanagimachi, MD, PhD Makoto Daimon, MD, PhD Fulminant Type 1 Diabetes in an 81-Year-Old Male with Rhabdomyolysis-Induced Acute Kidney Injury Successfully Withdrawn from Hemodialysis: A Case Report AACE Clinical Case Reports |
| title | Fulminant Type 1 Diabetes in an 81-Year-Old Male with Rhabdomyolysis-Induced Acute Kidney Injury Successfully Withdrawn from Hemodialysis: A Case Report |
| title_full | Fulminant Type 1 Diabetes in an 81-Year-Old Male with Rhabdomyolysis-Induced Acute Kidney Injury Successfully Withdrawn from Hemodialysis: A Case Report |
| title_fullStr | Fulminant Type 1 Diabetes in an 81-Year-Old Male with Rhabdomyolysis-Induced Acute Kidney Injury Successfully Withdrawn from Hemodialysis: A Case Report |
| title_full_unstemmed | Fulminant Type 1 Diabetes in an 81-Year-Old Male with Rhabdomyolysis-Induced Acute Kidney Injury Successfully Withdrawn from Hemodialysis: A Case Report |
| title_short | Fulminant Type 1 Diabetes in an 81-Year-Old Male with Rhabdomyolysis-Induced Acute Kidney Injury Successfully Withdrawn from Hemodialysis: A Case Report |
| title_sort | fulminant type 1 diabetes in an 81 year old male with rhabdomyolysis induced acute kidney injury successfully withdrawn from hemodialysis a case report |
| url | http://www.sciencedirect.com/science/article/pii/S2376060520302510 |
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