Etiology of end-stage liver cirrhosis impacts hepatic natural killer cell heterogenicity

Etiology of end-stage liver cirrhosis impacts hepatic natural killer cell heterogenicity

The natural killer (NK) cell population is a critical component of the innate immune compartment of the liver, and its functions are deeply affected by the surrounding environment. In the late stage of fibrosis, NK cells become dysfunctional, but the influence of disease etiology on NK cell behavior...

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Bibliographic Details
Main Authors: Ana C. Maretti-Mira, Matthew P. Salomon, Angela M. Hsu, Lily Dara, Lucy Golden-Mason
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-03-01
Series:Frontiers in Immunology
Subjects:
natural killer cells
innate lymphocyte cells
NASH
HCV
PSC
cirrhosis
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2023.1137034/full

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