Subcellular structural plasticity caused by the absence of the fast Ca2+ buffer calbindin D-28k in recurrent collaterals of cerebellar Purkinje neurons

Subcellular structural plasticity caused by the absence of the fast Ca2+ buffer calbindin D-28k in recurrent collaterals of cerebellar Purkinje neurons

Purkinje cells (PC) control spike timing of neighboring PC by their recurrent axon collaterals. These synapses underlie fast cerebellar oscillations and are characterized by a strong facilitation within a time window of <20 ms during paired-pulse protocols. PC express high levels of the fast Ca2+...

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Bibliographic Details
Main Authors: David eOrduz, Alain eBoom, David eGall, Jean-Pierre eBrion, Serge N Schiffmann, Beat eSchwaller
Format: Article
Language:English
Published: Frontiers Media S.A. 2014-11-01
Series:Frontiers in Cellular Neuroscience
Subjects:
Cerebellum
calcium buffer
synaptic cleft
calbindin D-28k
axonal recurrent collateral
synaptic bouton
Online Access:http://journal.frontiersin.org/Journal/10.3389/fncel.2014.00364/full

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