Inflammatory Signaling Pathways in Preleukemic and Leukemic Stem Cells

Inflammatory Signaling Pathways in Preleukemic and Leukemic Stem Cells

Hematopoietic stem cells (HSCs) are a rare subset of bone marrow cells that usually exist in a quiescent state, only entering the cell cycle to replenish the blood compartment, thereby limiting the potential for errors in replication. Inflammatory signals that are released in response to environment...

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Bibliographic Details
Main Authors: Shayda Hemmati, Tamanna Haque, Kira Gritsman
Format: Article
Language:English
Published: Frontiers Media S.A. 2017-11-01
Series:Frontiers in Oncology
Subjects:
inflammatory
preleukemic
leukemic stem cell
toll-like receptor
tumor necrosis factor
interferon
Online Access:http://journal.frontiersin.org/article/10.3389/fonc.2017.00265/full

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