Cushing's syndrome as a paraneoplastic feature of renal cell carcinoma: A case report

Cushing's syndrome has been believed to be a paraneoplastic syndrome of renal cell carcinomas. However, there appears to be a dearth of compelling evidence to substantiate this notion. The only eligible documentation of Cushing's syndrome due to ectopic adrenocorticotropic hormone secretio...

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Main Authors: Asaad Moradi, Nasrollah Abian, Behnam Shakiba, Kiarash Moradi, Leyla Arefian
Format: Article
Language:English
Published: Elsevier 2023-09-01
Series:Urology Case Reports
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2214442023001900
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author Asaad Moradi
Nasrollah Abian
Behnam Shakiba
Kiarash Moradi
Leyla Arefian
author_facet Asaad Moradi
Nasrollah Abian
Behnam Shakiba
Kiarash Moradi
Leyla Arefian
author_sort Asaad Moradi
collection DOAJ
description Cushing's syndrome has been believed to be a paraneoplastic syndrome of renal cell carcinomas. However, there appears to be a dearth of compelling evidence to substantiate this notion. The only eligible documentation of Cushing's syndrome due to ectopic adrenocorticotropic hormone secretion by renal cancer in English literature dates back to 1988, and it pertains to a deceased patient discovered during an autopsy. Here, we present the first case of Cushing's syndrome as a paraneoplastic feature of renal cancer which showed complete resolution following surgical removal of the tumor. Additionally, we conduct review of the literature on this particular subject.
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spelling doaj.art-46f1053a0813422cb67b66cb71e21f9d2023-09-09T04:55:30ZengElsevierUrology Case Reports2214-44202023-09-0150102504Cushing's syndrome as a paraneoplastic feature of renal cell carcinoma: A case reportAsaad Moradi0Nasrollah Abian1Behnam Shakiba2Kiarash Moradi3Leyla Arefian4Department of Urology, Firoozgar Hospital, School of Medicine, Iran University of Medical Sciences, Tehran, IranDepartment of Urology, 5 Azar Hospital, School of Medicine, Golestan University of Medical Sciences and Health Services, Gorgan, Iran; Corresponding author. Department of urology, 5 Azar Hospital, 5 Azar Blvd., Gorgan, Golestan province, Iran.Department of Urology, Firoozgar Hospital, School of Medicine, Iran University of Medical Sciences, Tehran, IranDepartment of Urology, Firoozgar Hospital, School of Medicine, Iran University of Medical Sciences, Tehran, IranDepartment of Pathology, Aban General Hospital, Tehran, IranCushing's syndrome has been believed to be a paraneoplastic syndrome of renal cell carcinomas. However, there appears to be a dearth of compelling evidence to substantiate this notion. The only eligible documentation of Cushing's syndrome due to ectopic adrenocorticotropic hormone secretion by renal cancer in English literature dates back to 1988, and it pertains to a deceased patient discovered during an autopsy. Here, we present the first case of Cushing's syndrome as a paraneoplastic feature of renal cancer which showed complete resolution following surgical removal of the tumor. Additionally, we conduct review of the literature on this particular subject.http://www.sciencedirect.com/science/article/pii/S2214442023001900Cushing's syndromeRCCACTHParaneoplastic syndrome
spellingShingle Asaad Moradi
Nasrollah Abian
Behnam Shakiba
Kiarash Moradi
Leyla Arefian
Cushing's syndrome as a paraneoplastic feature of renal cell carcinoma: A case report
Urology Case Reports
Cushing's syndrome
RCC
ACTH
Paraneoplastic syndrome
title Cushing's syndrome as a paraneoplastic feature of renal cell carcinoma: A case report
title_full Cushing's syndrome as a paraneoplastic feature of renal cell carcinoma: A case report
title_fullStr Cushing's syndrome as a paraneoplastic feature of renal cell carcinoma: A case report
title_full_unstemmed Cushing's syndrome as a paraneoplastic feature of renal cell carcinoma: A case report
title_short Cushing's syndrome as a paraneoplastic feature of renal cell carcinoma: A case report
title_sort cushing s syndrome as a paraneoplastic feature of renal cell carcinoma a case report
topic Cushing's syndrome
RCC
ACTH
Paraneoplastic syndrome
url http://www.sciencedirect.com/science/article/pii/S2214442023001900
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AT nasrollahabian cushingssyndromeasaparaneoplasticfeatureofrenalcellcarcinomaacasereport
AT behnamshakiba cushingssyndromeasaparaneoplasticfeatureofrenalcellcarcinomaacasereport
AT kiarashmoradi cushingssyndromeasaparaneoplasticfeatureofrenalcellcarcinomaacasereport
AT leylaarefian cushingssyndromeasaparaneoplasticfeatureofrenalcellcarcinomaacasereport