Comparison between the Effect of 810 nm and 940 nm Diode Laser Irradiation on Histopathological Changes in Iatrogenic Oral Ulcers: an Animal Study
Statement of the Problem: Considering the relatively high prevalence of oral mucosal ulcers, their fast healing is of significance. Purpose: This study aimed to histopathologically compare the effects of 810 nm and 940 nm diode laser on the healing of iatrogenic oral ulcers in rabbits. Materials...
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| Format: | Article |
| Language: | English |
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Shiraz University of Medical Sciences
2021-12-01
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| Series: | Journal of Dentistry |
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| Online Access: | https://dentjods.sums.ac.ir/article_47921_e379aa704fa913b06a7ed7bad4fa139e.pdf |
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| author | Hooman Ebrahimi Fatemeh Darvish Mojgan Alaeddini Shahroo Etemad-Moghadam |
| author_facet | Hooman Ebrahimi Fatemeh Darvish Mojgan Alaeddini Shahroo Etemad-Moghadam |
| author_sort | Hooman Ebrahimi |
| collection | DOAJ |
| description | Statement of the Problem: Considering the relatively high prevalence of oral mucosal ulcers, their fast healing is of significance.
Purpose: This study aimed to histopathologically compare the effects of 810 nm and 940 nm diode laser on the healing of iatrogenic oral ulcers in rabbits.
Materials and Method: In this single-blind experimental study, mucosal ulcers measuring 3mm in diameter and 1mm in depth were bilaterally created in the buccal mucosa of 18 rabbits using a biopsy punch. The defects were irradiated with 810 nm diode laser on the right side and 940 nm diode laser on the left side. Biopsy samples of the same depth were obtained from the ulcers on days 3 and 7 followed by histopathological analysis. The intensity of inflammation was determined on hematoxylin-eosin-stained sections using a four-point scale. Data were analyzed employing the Wilcoxon signed rank test.
Results: The degree of inflammation was not significantly different between the 810nm and 940nm diode laser groups on day 3; but on day 7, animals receiving 810 nm experienced a significantly lower degree of inflammation compared to those treated with 940 nm laser (p= 0.028).
Conclusion: When comparing 810- and 940-nm diode lasers, 810 nm irradiation significantly decreased the severity of inflammation in oral wounds created on the buccal mucosa of rabbits in a time-dependent manner. |
| first_indexed | 2024-12-19T20:55:55Z |
| format | Article |
| id | doaj.art-46f555ccbc13416599e25cb47a783ef8 |
| institution | Directory Open Access Journal |
| issn | 2345-6485 2345-6418 |
| language | English |
| last_indexed | 2024-12-19T20:55:55Z |
| publishDate | 2021-12-01 |
| publisher | Shiraz University of Medical Sciences |
| record_format | Article |
| series | Journal of Dentistry |
| spelling | doaj.art-46f555ccbc13416599e25cb47a783ef82022-12-21T20:05:57ZengShiraz University of Medical SciencesJournal of Dentistry2345-64852345-64182021-12-0122426727210.30476/DENTJODS.2021.86623.1202Comparison between the Effect of 810 nm and 940 nm Diode Laser Irradiation on Histopathological Changes in Iatrogenic Oral Ulcers: an Animal StudyHooman Ebrahimi 0Fatemeh Darvish 1Mojgan Alaeddini 2Shahroo Etemad-Moghadam 3Dept. of Oral Medicine, Dental Faculty, Islamic Azad University of Medical Sciences,Tehran, Iran. Oral and Maxillofacial Medicine Specialist, Tehran, Iran. Dental Research Center, Dentistry Research Institute, Tehran University of Medical Sciences, Tehran, Iran.Dental Research Center, Dentistry Research Institute, Tehran University of Medical Sciences, Tehran, Iran.Statement of the Problem: Considering the relatively high prevalence of oral mucosal ulcers, their fast healing is of significance. Purpose: This study aimed to histopathologically compare the effects of 810 nm and 940 nm diode laser on the healing of iatrogenic oral ulcers in rabbits. Materials and Method: In this single-blind experimental study, mucosal ulcers measuring 3mm in diameter and 1mm in depth were bilaterally created in the buccal mucosa of 18 rabbits using a biopsy punch. The defects were irradiated with 810 nm diode laser on the right side and 940 nm diode laser on the left side. Biopsy samples of the same depth were obtained from the ulcers on days 3 and 7 followed by histopathological analysis. The intensity of inflammation was determined on hematoxylin-eosin-stained sections using a four-point scale. Data were analyzed employing the Wilcoxon signed rank test. Results: The degree of inflammation was not significantly different between the 810nm and 940nm diode laser groups on day 3; but on day 7, animals receiving 810 nm experienced a significantly lower degree of inflammation compared to those treated with 940 nm laser (p= 0.028). Conclusion: When comparing 810- and 940-nm diode lasers, 810 nm irradiation significantly decreased the severity of inflammation in oral wounds created on the buccal mucosa of rabbits in a time-dependent manner.https://dentjods.sums.ac.ir/article_47921_e379aa704fa913b06a7ed7bad4fa139e.pdf810 nm diode laser; 940 nm diode laser; inflammation; oral ulcers; |
| spellingShingle | Hooman Ebrahimi Fatemeh Darvish Mojgan Alaeddini Shahroo Etemad-Moghadam Comparison between the Effect of 810 nm and 940 nm Diode Laser Irradiation on Histopathological Changes in Iatrogenic Oral Ulcers: an Animal Study Journal of Dentistry 810 nm diode laser; 940 nm diode laser; inflammation; oral ulcers; |
| title | Comparison between the Effect of 810 nm and 940 nm Diode Laser Irradiation on Histopathological Changes in Iatrogenic Oral Ulcers: an Animal Study |
| title_full | Comparison between the Effect of 810 nm and 940 nm Diode Laser Irradiation on Histopathological Changes in Iatrogenic Oral Ulcers: an Animal Study |
| title_fullStr | Comparison between the Effect of 810 nm and 940 nm Diode Laser Irradiation on Histopathological Changes in Iatrogenic Oral Ulcers: an Animal Study |
| title_full_unstemmed | Comparison between the Effect of 810 nm and 940 nm Diode Laser Irradiation on Histopathological Changes in Iatrogenic Oral Ulcers: an Animal Study |
| title_short | Comparison between the Effect of 810 nm and 940 nm Diode Laser Irradiation on Histopathological Changes in Iatrogenic Oral Ulcers: an Animal Study |
| title_sort | comparison between the effect of 810 nm and 940 nm diode laser irradiation on histopathological changes in iatrogenic oral ulcers an animal study |
| topic | 810 nm diode laser; 940 nm diode laser; inflammation; oral ulcers; |
| url | https://dentjods.sums.ac.ir/article_47921_e379aa704fa913b06a7ed7bad4fa139e.pdf |
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