Phytochemistry, Food Application, and Therapeutic Potential of the Medicinal Plant (<i>Withania coagulans</i>): A Review

Herbal plants have been utilized to treat and cure various health-related problems since ancient times. The use of Ayurvedic medicine is very significant because of its least reported side effects and host of advantages. <i>Withania coagulans</i> (Family; Solanaceae), a valuable medicina...

Full description

Bibliographic Details
Main Authors: Muhammad Issa Khan, Maria Maqsood, Raakia Anam Saeed, Amna Alam, Amna Sahar, Marek Kieliszek, Antoni Miecznikowski, Hafiz Shehzad Muzammil, Rana Muhammad Aadil
Format: Article
Language:English
Published: MDPI AG 2021-11-01
Series:Molecules
Subjects:
Online Access:https://www.mdpi.com/1420-3049/26/22/6881
_version_ 1797509145599934464
author Muhammad Issa Khan
Maria Maqsood
Raakia Anam Saeed
Amna Alam
Amna Sahar
Marek Kieliszek
Antoni Miecznikowski
Hafiz Shehzad Muzammil
Rana Muhammad Aadil
author_facet Muhammad Issa Khan
Maria Maqsood
Raakia Anam Saeed
Amna Alam
Amna Sahar
Marek Kieliszek
Antoni Miecznikowski
Hafiz Shehzad Muzammil
Rana Muhammad Aadil
author_sort Muhammad Issa Khan
collection DOAJ
description Herbal plants have been utilized to treat and cure various health-related problems since ancient times. The use of Ayurvedic medicine is very significant because of its least reported side effects and host of advantages. <i>Withania coagulans</i> (Family; Solanaceae), a valuable medicinal plant, has been used to cure abnormal cell growth, wasting disorders, neural as well as physical problems, diabetes mellitus, insomnia, acute and chronic hepatic ailments. This review provides critical insight regarding the phytochemistry, biological activities, and pharmacognostic properties of <i>W. coagulans</i>. It has been known to possess diuretic, anti-inflammatory, anti-bacterial, anti-fungal, cardio-protective, hepato-protective, hypoglycemic, anti-oxidative, and anti-mutagenic properties owing to the existence of withanolides, an active compound present in it. Apart from withanolides, <i>W. coagulans</i> also contains many phytochemicals such as flavonoids, tannins, and β-sterols. Several studies indicate that various parts of <i>W. coagulans</i> and their active constituents have numerous pharmacological and therapeutic properties and thus can be considered as a new drug therapy against multiple diseases.
first_indexed 2024-03-10T05:14:01Z
format Article
id doaj.art-46f710ef94904ca880f90875b917f80b
institution Directory Open Access Journal
issn 1420-3049
language English
last_indexed 2024-03-10T05:14:01Z
publishDate 2021-11-01
publisher MDPI AG
record_format Article
series Molecules
spelling doaj.art-46f710ef94904ca880f90875b917f80b2023-11-23T00:35:10ZengMDPI AGMolecules1420-30492021-11-012622688110.3390/molecules26226881Phytochemistry, Food Application, and Therapeutic Potential of the Medicinal Plant (<i>Withania coagulans</i>): A ReviewMuhammad Issa Khan0Maria Maqsood1Raakia Anam Saeed2Amna Alam3Amna Sahar4Marek Kieliszek5Antoni Miecznikowski6Hafiz Shehzad Muzammil7Rana Muhammad Aadil8National Institute of Food Science and Technology, University of Agriculture, Faisalabad 38000, PakistanNational Institute of Food Science and Technology, University of Agriculture, Faisalabad 38000, PakistanNational Institute of Food Science and Technology, University of Agriculture, Faisalabad 38000, PakistanNational Institute of Food Science and Technology, University of Agriculture, Faisalabad 38000, PakistanNational Institute of Food Science and Technology, University of Agriculture, Faisalabad 38000, PakistanDepartment of Food Biotechnology and Microbiology, Institute of Food Sciences, Warsaw University of Life Sciences—SGGW, Nowoursynowska 159 C, 02-776 Warsaw, PolandDepartment of Fermentation Technology, Prof. Waclaw Dabrowski Institute of Agricultural and Food Biotechnology—State Research Institute, Rakowiecka 36, 02-532 Warsaw, PolandNational Institute of Food Science and Technology, University of Agriculture, Faisalabad 38000, PakistanNational Institute of Food Science and Technology, University of Agriculture, Faisalabad 38000, PakistanHerbal plants have been utilized to treat and cure various health-related problems since ancient times. The use of Ayurvedic medicine is very significant because of its least reported side effects and host of advantages. <i>Withania coagulans</i> (Family; Solanaceae), a valuable medicinal plant, has been used to cure abnormal cell growth, wasting disorders, neural as well as physical problems, diabetes mellitus, insomnia, acute and chronic hepatic ailments. This review provides critical insight regarding the phytochemistry, biological activities, and pharmacognostic properties of <i>W. coagulans</i>. It has been known to possess diuretic, anti-inflammatory, anti-bacterial, anti-fungal, cardio-protective, hepato-protective, hypoglycemic, anti-oxidative, and anti-mutagenic properties owing to the existence of withanolides, an active compound present in it. Apart from withanolides, <i>W. coagulans</i> also contains many phytochemicals such as flavonoids, tannins, and β-sterols. Several studies indicate that various parts of <i>W. coagulans</i> and their active constituents have numerous pharmacological and therapeutic properties and thus can be considered as a new drug therapy against multiple diseases.https://www.mdpi.com/1420-3049/26/22/6881Ayurvedic propertiesdiureticphytochemistrypharmacognostic properties
spellingShingle Muhammad Issa Khan
Maria Maqsood
Raakia Anam Saeed
Amna Alam
Amna Sahar
Marek Kieliszek
Antoni Miecznikowski
Hafiz Shehzad Muzammil
Rana Muhammad Aadil
Phytochemistry, Food Application, and Therapeutic Potential of the Medicinal Plant (<i>Withania coagulans</i>): A Review
Molecules
Ayurvedic properties
diuretic
phytochemistry
pharmacognostic properties
title Phytochemistry, Food Application, and Therapeutic Potential of the Medicinal Plant (<i>Withania coagulans</i>): A Review
title_full Phytochemistry, Food Application, and Therapeutic Potential of the Medicinal Plant (<i>Withania coagulans</i>): A Review
title_fullStr Phytochemistry, Food Application, and Therapeutic Potential of the Medicinal Plant (<i>Withania coagulans</i>): A Review
title_full_unstemmed Phytochemistry, Food Application, and Therapeutic Potential of the Medicinal Plant (<i>Withania coagulans</i>): A Review
title_short Phytochemistry, Food Application, and Therapeutic Potential of the Medicinal Plant (<i>Withania coagulans</i>): A Review
title_sort phytochemistry food application and therapeutic potential of the medicinal plant i withania coagulans i a review
topic Ayurvedic properties
diuretic
phytochemistry
pharmacognostic properties
url https://www.mdpi.com/1420-3049/26/22/6881
work_keys_str_mv AT muhammadissakhan phytochemistryfoodapplicationandtherapeuticpotentialofthemedicinalplantiwithaniacoagulansiareview
AT mariamaqsood phytochemistryfoodapplicationandtherapeuticpotentialofthemedicinalplantiwithaniacoagulansiareview
AT raakiaanamsaeed phytochemistryfoodapplicationandtherapeuticpotentialofthemedicinalplantiwithaniacoagulansiareview
AT amnaalam phytochemistryfoodapplicationandtherapeuticpotentialofthemedicinalplantiwithaniacoagulansiareview
AT amnasahar phytochemistryfoodapplicationandtherapeuticpotentialofthemedicinalplantiwithaniacoagulansiareview
AT marekkieliszek phytochemistryfoodapplicationandtherapeuticpotentialofthemedicinalplantiwithaniacoagulansiareview
AT antonimiecznikowski phytochemistryfoodapplicationandtherapeuticpotentialofthemedicinalplantiwithaniacoagulansiareview
AT hafizshehzadmuzammil phytochemistryfoodapplicationandtherapeuticpotentialofthemedicinalplantiwithaniacoagulansiareview
AT ranamuhammadaadil phytochemistryfoodapplicationandtherapeuticpotentialofthemedicinalplantiwithaniacoagulansiareview