In vivo myocardial tissue characterization of all four chambers using high-resolution quantitative MRI
Quantitative native T1 Mapping of the myocardium without the application of contrast agents can be used to detect fibrosis in the left ventricle. Spatial resolution of standard native T1 mapping is limited by cardiac motion and hence is not sufficient to resolve small myocardial structures, such as...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
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De Gruyter
2018-09-01
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| Series: | Current Directions in Biomedical Engineering |
| Subjects: | |
| Online Access: | https://doi.org/10.1515/cdbme-2018-0064 |
| _version_ | 1811324119863525376 |
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| author | Becker Kirsten M. Schulz-Menger Jeanette Schaeffter Tobias Kolbitsch Christoph |
| author_facet | Becker Kirsten M. Schulz-Menger Jeanette Schaeffter Tobias Kolbitsch Christoph |
| author_sort | Becker Kirsten M. |
| collection | DOAJ |
| description | Quantitative native T1 Mapping of the myocardium without the application of contrast agents can be used to detect fibrosis in the left ventricle. Spatial resolution of standard native T1 mapping is limited by cardiac motion and hence is not sufficient to resolve small myocardial structures, such as the right ventricle and the atria. Here, we present a novel MR approach which provides cardiac motion information and native T1 maps from the same data. Motion information is utilized to optimize data selection for T1 mapping and a model-based iterative reconstruction scheme ensures high-resolution T1 maps for the entire heart. Feasibility of the approach was demonstrated in three healthy volunteers. In the T1 maps, the myocardium of all four chambers can be visualized and T1 values of the left atrium and right chambers were comparable to left ventricular T1 values. |
| first_indexed | 2024-04-13T14:08:50Z |
| format | Article |
| id | doaj.art-46f97eef386b49adb1ac2bad471c3c59 |
| institution | Directory Open Access Journal |
| issn | 2364-5504 |
| language | English |
| last_indexed | 2024-04-13T14:08:50Z |
| publishDate | 2018-09-01 |
| publisher | De Gruyter |
| record_format | Article |
| series | Current Directions in Biomedical Engineering |
| spelling | doaj.art-46f97eef386b49adb1ac2bad471c3c592022-12-22T02:43:50ZengDe GruyterCurrent Directions in Biomedical Engineering2364-55042018-09-014126326610.1515/cdbme-2018-0064cdbme-2018-0064In vivo myocardial tissue characterization of all four chambers using high-resolution quantitative MRIBecker Kirsten M.0Schulz-Menger Jeanette1Schaeffter Tobias2Kolbitsch Christoph3Physikalisch- Technische Bundesanstalt (PTB), Abbestr. 2-12,Berlin, GermanyCharité Medical Faculty University Medicine, Working Group on Cardiovascular Magnetic Resonance, Experimental and Clinical Research Center (ECRC), DZHK partner siteBerlin, GermanyPhysikalisch- Technische Bundesanstalt (PTB), Braunschweig andBerlin, GermanyPhysikalisch- Technische Bundesanstalt (PTB), Braunschweig andBerlin, GermanyQuantitative native T1 Mapping of the myocardium without the application of contrast agents can be used to detect fibrosis in the left ventricle. Spatial resolution of standard native T1 mapping is limited by cardiac motion and hence is not sufficient to resolve small myocardial structures, such as the right ventricle and the atria. Here, we present a novel MR approach which provides cardiac motion information and native T1 maps from the same data. Motion information is utilized to optimize data selection for T1 mapping and a model-based iterative reconstruction scheme ensures high-resolution T1 maps for the entire heart. Feasibility of the approach was demonstrated in three healthy volunteers. In the T1 maps, the myocardium of all four chambers can be visualized and T1 values of the left atrium and right chambers were comparable to left ventricular T1 values.https://doi.org/10.1515/cdbme-2018-0064t1 mappingmyocardial tissue characterizationmagnetic resonance imaging |
| spellingShingle | Becker Kirsten M. Schulz-Menger Jeanette Schaeffter Tobias Kolbitsch Christoph In vivo myocardial tissue characterization of all four chambers using high-resolution quantitative MRI Current Directions in Biomedical Engineering t1 mapping myocardial tissue characterization magnetic resonance imaging |
| title | In vivo myocardial tissue characterization of all four chambers using high-resolution quantitative MRI |
| title_full | In vivo myocardial tissue characterization of all four chambers using high-resolution quantitative MRI |
| title_fullStr | In vivo myocardial tissue characterization of all four chambers using high-resolution quantitative MRI |
| title_full_unstemmed | In vivo myocardial tissue characterization of all four chambers using high-resolution quantitative MRI |
| title_short | In vivo myocardial tissue characterization of all four chambers using high-resolution quantitative MRI |
| title_sort | in vivo myocardial tissue characterization of all four chambers using high resolution quantitative mri |
| topic | t1 mapping myocardial tissue characterization magnetic resonance imaging |
| url | https://doi.org/10.1515/cdbme-2018-0064 |
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