Immune complex–driven neutrophil activation and BAFF release: a link to B cell responses in SLE
Objective The role of neutrophils in driving pathogenic B cell responses in SLE is not fully understood. In this study, we explored the link between immune complex (IC)–driven neutrophil activation, the release of B cell pro-survival factor BAFF and B cell activation using SLE clinical samples.Metho...
Main Authors: | Ting Wang, Christian Lood, Sladjana Skopelja-Gardner, Andrew Vasconcellos, John Marken, Natalia V Giltiay |
---|---|
Format: | Article |
Language: | English |
Published: |
BMJ Publishing Group
2022-07-01
|
Series: | Lupus Science and Medicine |
Online Access: | https://lupus.bmj.com/content/9/1/e000709.full |
Similar Items
-
B cell-activating factor (BAFF) from dendritic cells, monocytes and neutrophils is required for B cell maturation and autoantibody production in SLE-like autoimmune disease
by: Daniela Giordano, et al.
Published: (2023-02-01) -
SLE and alpha-SLE driven by Levy processes
by: Guan, Q, et al.
Published: (2008) -
Inhibition of Membrane-Bound BAFF by the Anti-BAFF Antibody Belimumab
by: Christine Kowalczyk-Quintas, et al.
Published: (2018-11-01) -
deltaBAFF, a splice isoform of BAFF, opposes full-length BAFF activity in vivo in transgenic mouse models.
by: Gavin, A, et al.
Published: (2005) -
P17 Autophagy- based unconventional secretion of B cell activating factor (BAFF) by monocytes in Systemic Lupus Erythematosus (SLE)
by: Prodromos Sidiropoulos, et al.
Published: (2024-03-01)