Regulation of Platelet-Derived ADAM17: A Biomarker Approach for Breast Cancer?

Regulation of Platelet-Derived ADAM17: A Biomarker Approach for Breast Cancer?

Tumor progression and metastasis are critically dependent on the tumor microenvironment. A disintegrin and metalloproteinase 17 (ADAM17) is associated with shedding of several substrates involved in tumor progression and known to be expressed by platelets of healthy donors and patients with solid tu...

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Bibliographic Details
Main Authors: Yanjun Zhou, Jonas S. Heitmann, Korbinian N. Kropp, Martina Hinterleitner, André Koch, Andreas D. Hartkopf, Helmut R. Salih, Clemens Hinterleitner, Stefanie Maurer
Format: Article
Language:English
Published: MDPI AG 2021-06-01
Series:Diagnostics
Subjects:
platelets
breast cancer
biomarker
ADAM17
metastasis
Online Access:https://www.mdpi.com/2075-4418/11/7/1188

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