Negative Effects of Diffuse Idiopathic Skeletal Hyperostosis on Bone Fusion after Transforaminal Lumbar Interbody Fusion
Study Design This study adopted a retrospective cohort study design. Purpose This study aimed to clarify the influence of diffuse idiopathic skeletal hyperostosis (DISH) on bone fusion after transforaminal lumbar interbody fusion (TLIF). Overview of Literature The negative effects of DISH on lumbar...
| Main Authors: | , , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
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Korean Spine Society
2023-10-01
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| Series: | Asian Spine Journal |
| Subjects: | |
| Online Access: | http://www.asianspinejournal.org/upload/pdf/asj-2022-0453.pdf |
| _version_ | 1797644477250142208 |
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| author | Shusuke Hagihara Hideki Ohta Jun Tanaka Teruaki Shiokawa Yoshikuni Kida Yohei Iguchi Masato Tatsumi Ryo Shibata Kenichi Tahara Tatsuya Shibata Kyoichi Sanada Takuaki Ymamoto |
| author_facet | Shusuke Hagihara Hideki Ohta Jun Tanaka Teruaki Shiokawa Yoshikuni Kida Yohei Iguchi Masato Tatsumi Ryo Shibata Kenichi Tahara Tatsuya Shibata Kyoichi Sanada Takuaki Ymamoto |
| author_sort | Shusuke Hagihara |
| collection | DOAJ |
| description | Study Design This study adopted a retrospective cohort study design. Purpose This study aimed to clarify the influence of diffuse idiopathic skeletal hyperostosis (DISH) on bone fusion after transforaminal lumbar interbody fusion (TLIF). Overview of Literature The negative effects of DISH on lumbar degenerative diseases have been reported, and DISH may be involved in the onset and severity of lumbar spinal canal stenosis. Patients with DISH have significantly more reoperations after posterior lumbar fusion, including TLIF. However, the effects of DISH on bone fusion after TLIF have not been reported. Methods The medical records of patients with intervertebral TLIF from 2012 to 2018 were retrospectively examined. The patients were divided into those with fusion and those with pseudoarthrosis, and the following data were compared: age, sex, DISH, diabetes mellitus, smoking, drinking, albumin levels, body mass index ≥30 kg/m2, and L5/S fixation. Statistical analyses were performed using regression models. Results In this study, 180 patients (78.6%) had fusion and 49 patients (21.4%) had pseudoarthrosis. The number of patients with DISH was significantly higher in the pseudoarthrosis group than in the fusion group (36.7% and 21.7%, respectively; univariate p=0.031, multivariate p=0.019). No significant differences in age, sex, diabetes mellitus, smoking, drinking, albumin levels, body mass index ≥30 kg/m2, and L5/S fixation were observed between the two groups. The risk factors for bone fusion were statistically analyzed in 57 patients with DISH. DISH with a caudal end below Th11 was an independent risk factor for pseudoarthrosis (univariate p=0.011, multivariate p=0.033). Conclusions DISH is an independent risk factor for pseudoarthrosis after one intervertebral TLIF, and DISH with a caudal end below Th11 is associated with a higher risk of pseudoarthrosis than DISH without a caudal end below Th11. |
| first_indexed | 2024-03-11T14:31:01Z |
| format | Article |
| id | doaj.art-4703d5511d6343c2a9a008fe7dc23974 |
| institution | Directory Open Access Journal |
| issn | 1976-1902 1976-7846 |
| language | English |
| last_indexed | 2024-03-11T14:31:01Z |
| publishDate | 2023-10-01 |
| publisher | Korean Spine Society |
| record_format | Article |
| series | Asian Spine Journal |
| spelling | doaj.art-4703d5511d6343c2a9a008fe7dc239742023-10-31T08:19:30ZengKorean Spine SocietyAsian Spine Journal1976-19021976-78462023-10-0117581882510.31616/asj.2022.04531566Negative Effects of Diffuse Idiopathic Skeletal Hyperostosis on Bone Fusion after Transforaminal Lumbar Interbody FusionShusuke Hagihara0Hideki Ohta1Jun Tanaka2Teruaki Shiokawa3Yoshikuni Kida4Yohei Iguchi5Masato Tatsumi6Ryo Shibata7Kenichi Tahara8Tatsuya Shibata9Kyoichi Sanada10Takuaki Ymamoto11 Department of Orthopeadics Surgery, Faculty of Medicine, Fukuoka University, Fukuoka, Japan Oita Orthopaedic Hospital, Oita, Japan Department of Orthopeadics Surgery, Faculty of Medicine, Fukuoka University, Fukuoka, Japan Department of Orthopeadics Surgery, Faculty of Medicine, Fukuoka University, Fukuoka, Japan Oita Orthopaedic Hospital, Oita, Japan Oita Orthopaedic Hospital, Oita, Japan Oita Orthopaedic Hospital, Oita, Japan Department of Orthopeadics Surgery, Faculty of Medicine, Fukuoka University, Fukuoka, Japan Oita Orthopaedic Hospital, Oita, Japan Department of Orthopeadics Surgery, Faculty of Medicine, Fukuoka University, Fukuoka, Japan Department of Orthopeadics Surgery, Faculty of Medicine, Fukuoka University, Fukuoka, Japan Department of Orthopeadics Surgery, Faculty of Medicine, Fukuoka University, Fukuoka, JapanStudy Design This study adopted a retrospective cohort study design. Purpose This study aimed to clarify the influence of diffuse idiopathic skeletal hyperostosis (DISH) on bone fusion after transforaminal lumbar interbody fusion (TLIF). Overview of Literature The negative effects of DISH on lumbar degenerative diseases have been reported, and DISH may be involved in the onset and severity of lumbar spinal canal stenosis. Patients with DISH have significantly more reoperations after posterior lumbar fusion, including TLIF. However, the effects of DISH on bone fusion after TLIF have not been reported. Methods The medical records of patients with intervertebral TLIF from 2012 to 2018 were retrospectively examined. The patients were divided into those with fusion and those with pseudoarthrosis, and the following data were compared: age, sex, DISH, diabetes mellitus, smoking, drinking, albumin levels, body mass index ≥30 kg/m2, and L5/S fixation. Statistical analyses were performed using regression models. Results In this study, 180 patients (78.6%) had fusion and 49 patients (21.4%) had pseudoarthrosis. The number of patients with DISH was significantly higher in the pseudoarthrosis group than in the fusion group (36.7% and 21.7%, respectively; univariate p=0.031, multivariate p=0.019). No significant differences in age, sex, diabetes mellitus, smoking, drinking, albumin levels, body mass index ≥30 kg/m2, and L5/S fixation were observed between the two groups. The risk factors for bone fusion were statistically analyzed in 57 patients with DISH. DISH with a caudal end below Th11 was an independent risk factor for pseudoarthrosis (univariate p=0.011, multivariate p=0.033). Conclusions DISH is an independent risk factor for pseudoarthrosis after one intervertebral TLIF, and DISH with a caudal end below Th11 is associated with a higher risk of pseudoarthrosis than DISH without a caudal end below Th11.http://www.asianspinejournal.org/upload/pdf/asj-2022-0453.pdfthoracolumbar transition regiondiffuse idiopathic skeletal hyperostosisdish with a caudal end below th11pseudoarthrosistransforaminal lumbar interbody fusion |
| spellingShingle | Shusuke Hagihara Hideki Ohta Jun Tanaka Teruaki Shiokawa Yoshikuni Kida Yohei Iguchi Masato Tatsumi Ryo Shibata Kenichi Tahara Tatsuya Shibata Kyoichi Sanada Takuaki Ymamoto Negative Effects of Diffuse Idiopathic Skeletal Hyperostosis on Bone Fusion after Transforaminal Lumbar Interbody Fusion Asian Spine Journal thoracolumbar transition region diffuse idiopathic skeletal hyperostosis dish with a caudal end below th11 pseudoarthrosis transforaminal lumbar interbody fusion |
| title | Negative Effects of Diffuse Idiopathic Skeletal Hyperostosis on Bone Fusion after Transforaminal Lumbar Interbody Fusion |
| title_full | Negative Effects of Diffuse Idiopathic Skeletal Hyperostosis on Bone Fusion after Transforaminal Lumbar Interbody Fusion |
| title_fullStr | Negative Effects of Diffuse Idiopathic Skeletal Hyperostosis on Bone Fusion after Transforaminal Lumbar Interbody Fusion |
| title_full_unstemmed | Negative Effects of Diffuse Idiopathic Skeletal Hyperostosis on Bone Fusion after Transforaminal Lumbar Interbody Fusion |
| title_short | Negative Effects of Diffuse Idiopathic Skeletal Hyperostosis on Bone Fusion after Transforaminal Lumbar Interbody Fusion |
| title_sort | negative effects of diffuse idiopathic skeletal hyperostosis on bone fusion after transforaminal lumbar interbody fusion |
| topic | thoracolumbar transition region diffuse idiopathic skeletal hyperostosis dish with a caudal end below th11 pseudoarthrosis transforaminal lumbar interbody fusion |
| url | http://www.asianspinejournal.org/upload/pdf/asj-2022-0453.pdf |
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