STAT3 and p53: Dual Target for Cancer Therapy

The tumor suppressor p53 is considered the “guardian of the genome” that can protect cells against cancer by inducing cell cycle arrest followed by cell death. However, STAT3 is constitutively activated in several human cancers and plays crucial roles in promoting cancer cell proliferation and survi...

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Bibliographic Details
Main Authors: Thu-Huyen Pham, Hyo-Min Park, Jinju Kim, Jin Tae Hong, Do-Young Yoon
Format: Article
Language:English
Published: MDPI AG 2020-12-01
Series:Biomedicines
Subjects:
Online Access:https://www.mdpi.com/2227-9059/8/12/637