Cardiomyocyte-Targeting Peptide to Deliver Amiodarone
Background: Amiodarone is underutilized due to significant off-target toxicities. We hypothesized that targeted delivery to the heart would lead to the lowering of the dose by utilizing a cardiomyocyte-targeting peptide (CTP), a cell-penetrating peptide identified by our prior phage display work. Me...
Main Authors: | Maliha Zahid, Beth Weber, Ray Yurko, Kazi Islam, Vaishavi Agrawal, Jack Lopuszynski, Hisato Yagi, Guy Salama |
---|---|
Format: | Article |
Language: | English |
Published: |
MDPI AG
2023-08-01
|
Series: | Pharmaceutics |
Subjects: | |
Online Access: | https://www.mdpi.com/1999-4923/15/8/2107 |
Similar Items
-
Conjugation of amiodarone to a novel cardiomyocyte cell penetrating peptide for potential targeted delivery to the heart
by: Ray Yurko, et al.
Published: (2023-07-01) -
CARDIAC ARRHYTHMIAS IN MEDICAL PRACTICE: CLINICAL CASE OF AMIODARONE-INDUCED THYROTOXICOSIS TYPE 2 AS A CAUSE OF RECURRENT ATRIAL FIBRILLATION
by: O. V. Gaisenok
Published: (2016-01-01) -
Comparative efficacy of amiodarone with ivabradin combination or amiodarone with bisoprolol combination in the prevention of atrial fibrillation recurrence in pa- tients with left ventricular diastolic dysfunction
by: K. G. Adamyan, et al.
Published: (2015-11-01) -
Amiodarone-Induced Pulmonary Toxicity in a Patient With Paroxysmal Atrial Fibrillation and Recurrence of Pulmonary Toxicity
by: Nuri Köse, et al.
Published: (2022-01-01) -
SIDE EFFECTS OF PROLONGED ANTIARRHYTHMIC THERAPY WITH AMIODARONE
by: N P Dorofeeva, et al.
Published: (2017-03-01)